Quality of Life Assessment in Patients with Behçet’s Disease using the Persian Version of the Leeds BD-QoL Questionnaire
Background: Behçet’s disease (BD) can negatively impact the quality of life (QoL) of the affected patients. The present study aimed to assess the QoL of BD patients using the Leeds BD-QoL and compare its results with the WHOQOL-BREF questionnaire.<br />Methods: In the present cross-sectional s...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2020-09-01
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| Series: | Iranian Journal of Medical Sciences |
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| Online Access: | https://ijms.sums.ac.ir/article_46740_481939df11807577d417db7624277f8b.pdf |
| _version_ | 1819266089628991488 |
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| author | Elham Aflaki Saman Farahangiz Alireza Salehi |
| author_facet | Elham Aflaki Saman Farahangiz Alireza Salehi |
| author_sort | Elham Aflaki |
| collection | DOAJ |
| description | Background: Behçet’s disease (BD) can negatively impact the quality of life (QoL) of the affected patients. The present study aimed to assess the QoL of BD patients using the Leeds BD-QoL and compare its results with the WHOQOL-BREF questionnaire.<br />Methods: In the present cross-sectional study, 179 BD patients and 304 healthy individuals (the control group) were recruited in Shiraz, 2017. The Persian version of the Leeds BD-QoL and WHOQOL-BREF questionnaires were used to assess the QoL of patients with BD. The QoL in the patient and control groups was compared after controlling the effect of some variables (age, sex, marital status, and educational level) using the multiple linear regression analysis. Spearman’s correlation coefficient was calculated for the Leeds BD-QoL and WHOQOL-BREF scores. Disease activity was measured using the Behçet’s Disease Current Activity Form. All the statistical analysis was performed using SPSS software (version 21.0). P<0.05 was considered statistically significant.<br />Results: The mean of the Leeds BD-QoL total score in the patient group was 12.3±8.7. The control group had significantly higher scores in the WHOQOL-BREF total score and the physical health and psychological health domains compared with the patient group; mean difference of 10.24, 10.8, and 4.62, respectively (P<0.001). The Spearman’s correlation coefficient for the Leeds BD-QoL score and WHOQOL-BREF total score and its domains (physical health, psychological health, social relationships, and environment) was -0.669, -0.713, -0.714, -0.536, and -0.550, respectively. The disease activity score was correlated with the Leeds BD-QoL score (r=0.361, P<0.001).<br />Conclusion: BD patients had a lower QoL than healthy individuals, specifically in the physical health and psychological health domains. An increase in disease activity and severity was associated with a reduced QoL. The Persian version of the Leeds BD-QoL questionnaire had an acceptable correlation with the WHOQOL-BREF questionnaire. |
| first_indexed | 2024-12-23T20:55:44Z |
| format | Article |
| id | doaj.art-360f98392ae142deb642e93ab18da07c |
| institution | Directory Open Access Journal |
| issn | 0253-0716 1735-3688 |
| language | English |
| last_indexed | 2024-12-23T20:55:44Z |
| publishDate | 2020-09-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Medical Sciences |
| spelling | doaj.art-360f98392ae142deb642e93ab18da07c2022-12-21T17:31:31ZengShiraz University of Medical SciencesIranian Journal of Medical Sciences0253-07161735-36882020-09-0145535235810.30476/ijms.2020.72634.046740Quality of Life Assessment in Patients with Behçet’s Disease using the Persian Version of the Leeds BD-QoL QuestionnaireElham Aflaki0Saman Farahangiz1Alireza Salehi2Department of Rheumatology, Shiraz University of Medical Sciences, Shiraz, IranCommunity Medicine Specialist, Department of MPH, Shiraz University of Medical Sciences, Shiraz, IranResearch Center for Traditional Medicine and History of Medicine, Shiraz University of Medical Sciences, Shiraz, IranBackground: Behçet’s disease (BD) can negatively impact the quality of life (QoL) of the affected patients. The present study aimed to assess the QoL of BD patients using the Leeds BD-QoL and compare its results with the WHOQOL-BREF questionnaire.<br />Methods: In the present cross-sectional study, 179 BD patients and 304 healthy individuals (the control group) were recruited in Shiraz, 2017. The Persian version of the Leeds BD-QoL and WHOQOL-BREF questionnaires were used to assess the QoL of patients with BD. The QoL in the patient and control groups was compared after controlling the effect of some variables (age, sex, marital status, and educational level) using the multiple linear regression analysis. Spearman’s correlation coefficient was calculated for the Leeds BD-QoL and WHOQOL-BREF scores. Disease activity was measured using the Behçet’s Disease Current Activity Form. All the statistical analysis was performed using SPSS software (version 21.0). P<0.05 was considered statistically significant.<br />Results: The mean of the Leeds BD-QoL total score in the patient group was 12.3±8.7. The control group had significantly higher scores in the WHOQOL-BREF total score and the physical health and psychological health domains compared with the patient group; mean difference of 10.24, 10.8, and 4.62, respectively (P<0.001). The Spearman’s correlation coefficient for the Leeds BD-QoL score and WHOQOL-BREF total score and its domains (physical health, psychological health, social relationships, and environment) was -0.669, -0.713, -0.714, -0.536, and -0.550, respectively. The disease activity score was correlated with the Leeds BD-QoL score (r=0.361, P<0.001).<br />Conclusion: BD patients had a lower QoL than healthy individuals, specifically in the physical health and psychological health domains. An increase in disease activity and severity was associated with a reduced QoL. The Persian version of the Leeds BD-QoL questionnaire had an acceptable correlation with the WHOQOL-BREF questionnaire.https://ijms.sums.ac.ir/article_46740_481939df11807577d417db7624277f8b.pdfbehçet’s diseasequality of lifeleeds bd-qol |
| spellingShingle | Elham Aflaki Saman Farahangiz Alireza Salehi Quality of Life Assessment in Patients with Behçet’s Disease using the Persian Version of the Leeds BD-QoL Questionnaire Iranian Journal of Medical Sciences behçet’s disease quality of life leeds bd-qol |
| title | Quality of Life Assessment in Patients with Behçet’s Disease using the Persian Version of the Leeds BD-QoL Questionnaire |
| title_full | Quality of Life Assessment in Patients with Behçet’s Disease using the Persian Version of the Leeds BD-QoL Questionnaire |
| title_fullStr | Quality of Life Assessment in Patients with Behçet’s Disease using the Persian Version of the Leeds BD-QoL Questionnaire |
| title_full_unstemmed | Quality of Life Assessment in Patients with Behçet’s Disease using the Persian Version of the Leeds BD-QoL Questionnaire |
| title_short | Quality of Life Assessment in Patients with Behçet’s Disease using the Persian Version of the Leeds BD-QoL Questionnaire |
| title_sort | quality of life assessment in patients with behcet s disease using the persian version of the leeds bd qol questionnaire |
| topic | behçet’s disease quality of life leeds bd-qol |
| url | https://ijms.sums.ac.ir/article_46740_481939df11807577d417db7624277f8b.pdf |
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