Expression of lectins in nonspecific ulcerative colitis

Purpose: To analyze the expression of lectins in mucosa of a colon in patients with ulcerative colitis (UC), depending on the duration, severity, location and activity of the inflammatory process. Materials and methods: A total of 48 patients with ulcerative colitis and 15 healthy people have been e...

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Main Authors: Maslyakova G.N., Kashkina E.I., Markova А.А.
Format: Article
Language:Russian
Published: Saratov State Medical University 2012-12-01
Series:Саратовский научно-медицинский журнал
Subjects:
Online Access:http://www.ssmj.ru/system/files/201204-937-942.pdf
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author Maslyakova G.N.
Kashkina E.I.
Markova А.А.
author_facet Maslyakova G.N.
Kashkina E.I.
Markova А.А.
author_sort Maslyakova G.N.
collection DOAJ
description Purpose: To analyze the expression of lectins in mucosa of a colon in patients with ulcerative colitis (UC), depending on the duration, severity, location and activity of the inflammatory process. Materials and methods: A total of 48 patients with ulcerative colitis and 15 healthy people have been examined. The expression of specific lectins has been determined in mucosa of colon. Results: in healthy patients the expression of the studied lectins has not been observed. In patients with ulcerative colitis there have been differences in the expression of the wheat ovaries lectin. Conclusion: In patients with ulcerative colitis the dependence of expression of the wheat ovaries lectin, WGA-isotropic to N-acetylglucosamine, on the severity and activity of the inflammatory process has been determined.
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spelling doaj.art-3610e2ae239e446ea779cc62ea673ec92022-12-21T20:24:57ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал1995-00392076-25182012-12-0184937942Expression of lectins in nonspecific ulcerative colitisMaslyakova G.N.Kashkina E.I.Markova А.А.Purpose: To analyze the expression of lectins in mucosa of a colon in patients with ulcerative colitis (UC), depending on the duration, severity, location and activity of the inflammatory process. Materials and methods: A total of 48 patients with ulcerative colitis and 15 healthy people have been examined. The expression of specific lectins has been determined in mucosa of colon. Results: in healthy patients the expression of the studied lectins has not been observed. In patients with ulcerative colitis there have been differences in the expression of the wheat ovaries lectin. Conclusion: In patients with ulcerative colitis the dependence of expression of the wheat ovaries lectin, WGA-isotropic to N-acetylglucosamine, on the severity and activity of the inflammatory process has been determined.http://www.ssmj.ru/system/files/201204-937-942.pdflectinsnonspecific ulcerative colitis
spellingShingle Maslyakova G.N.
Kashkina E.I.
Markova А.А.
Expression of lectins in nonspecific ulcerative colitis
Саратовский научно-медицинский журнал
lectins
nonspecific ulcerative colitis
title Expression of lectins in nonspecific ulcerative colitis
title_full Expression of lectins in nonspecific ulcerative colitis
title_fullStr Expression of lectins in nonspecific ulcerative colitis
title_full_unstemmed Expression of lectins in nonspecific ulcerative colitis
title_short Expression of lectins in nonspecific ulcerative colitis
title_sort expression of lectins in nonspecific ulcerative colitis
topic lectins
nonspecific ulcerative colitis
url http://www.ssmj.ru/system/files/201204-937-942.pdf
work_keys_str_mv AT maslyakovagn expressionoflectinsinnonspecificulcerativecolitis
AT kashkinaei expressionoflectinsinnonspecificulcerativecolitis
AT markovaaa expressionoflectinsinnonspecificulcerativecolitis