Long-term results of complete clinical and pathologic regression in patients with breast cancer
The article presents the results of analysis of long-term treatment outcomes of 162 patients who received neoadjuvant chemotherapy for breast cancer based on City Clinical Hospital No. 40 of Ekaterinburg. ER-negative status, triple-negative subtype of tumor and lymph node negative status were found...
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Format: | Article |
Language: | Russian |
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ABV-press
2016-09-01
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Series: | Опухоли женской репродуктивной системы |
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Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/490 |
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author | S. M. Demidov D. A. Demidov M. A. Zafirova |
author_facet | S. M. Demidov D. A. Demidov M. A. Zafirova |
author_sort | S. M. Demidov |
collection | DOAJ |
description | The article presents the results of analysis of long-term treatment outcomes of 162 patients who received neoadjuvant chemotherapy for breast cancer based on City Clinical Hospital No. 40 of Ekaterinburg. ER-negative status, triple-negative subtype of tumor and lymph node negative status were found to be significant predictive factors of complete tumor regression. In studying long-term results of the treatment it was showed that negative status of lymph nodes significantly predicts improvement in relapse-free survival, while the surgical treatment does not increase relapse-free survival time in case of complete tumor regression. |
first_indexed | 2024-04-10T01:56:14Z |
format | Article |
id | doaj.art-3612ff26ad6b44a094e5f87d68a35152 |
institution | Directory Open Access Journal |
issn | 1994-4098 1999-8627 |
language | Russian |
last_indexed | 2025-03-14T08:25:49Z |
publishDate | 2016-09-01 |
publisher | ABV-press |
record_format | Article |
series | Опухоли женской репродуктивной системы |
spelling | doaj.art-3612ff26ad6b44a094e5f87d68a351522025-03-02T13:05:33ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272016-09-01122222510.17650/1994-4098-2016-12-2-22-25495Long-term results of complete clinical and pathologic regression in patients with breast cancerS. M. Demidov0D. A. Demidov1M. A. Zafirova2Municipal autonomous institution “City Clinical Hospital No. 40”; Federal State Educational Institution of Higher Education “Ural State Medical University” of the Ministry of Health of RussiaMunicipal autonomous institution “City Clinical Hospital No. 40”; Federal State Educational Institution of Higher Education “Ural State Medical University” of the Ministry of Health of RussiaFederal State Educational Institution of Higher Education “Ural State Medical University” of the Ministry of Health of RussiaThe article presents the results of analysis of long-term treatment outcomes of 162 patients who received neoadjuvant chemotherapy for breast cancer based on City Clinical Hospital No. 40 of Ekaterinburg. ER-negative status, triple-negative subtype of tumor and lymph node negative status were found to be significant predictive factors of complete tumor regression. In studying long-term results of the treatment it was showed that negative status of lymph nodes significantly predicts improvement in relapse-free survival, while the surgical treatment does not increase relapse-free survival time in case of complete tumor regression.https://ojrs.abvpress.ru/ojrs/article/view/490breast cancerneoadjuvant chemotherapytumor regressionpredictive factorsrelapse-free survival |
spellingShingle | S. M. Demidov D. A. Demidov M. A. Zafirova Long-term results of complete clinical and pathologic regression in patients with breast cancer Опухоли женской репродуктивной системы breast cancer neoadjuvant chemotherapy tumor regression predictive factors relapse-free survival |
title | Long-term results of complete clinical and pathologic regression in patients with breast cancer |
title_full | Long-term results of complete clinical and pathologic regression in patients with breast cancer |
title_fullStr | Long-term results of complete clinical and pathologic regression in patients with breast cancer |
title_full_unstemmed | Long-term results of complete clinical and pathologic regression in patients with breast cancer |
title_short | Long-term results of complete clinical and pathologic regression in patients with breast cancer |
title_sort | long term results of complete clinical and pathologic regression in patients with breast cancer |
topic | breast cancer neoadjuvant chemotherapy tumor regression predictive factors relapse-free survival |
url | https://ojrs.abvpress.ru/ojrs/article/view/490 |
work_keys_str_mv | AT smdemidov longtermresultsofcompleteclinicalandpathologicregressioninpatientswithbreastcancer AT dademidov longtermresultsofcompleteclinicalandpathologicregressioninpatientswithbreastcancer AT mazafirova longtermresultsofcompleteclinicalandpathologicregressioninpatientswithbreastcancer |