Mycolactone cytotoxicity in Schwann cells could explain nerve damage in Buruli ulcer.
Buruli ulcer is a chronic painless skin disease caused by Mycobacterium ulcerans. The local nerve damage induced by M. ulcerans invasion is similar to the nerve damage evoked by the injection of mycolactone in a Buruli ulcer mouse model. In order to elucidate the mechanism of this nerve damage, we t...
Main Authors: | Junichiro En, Sho Kitamoto, Akira Kawashima, Suguru Yonezawa, Yoshito Kishi, Norihisa Ishii, Masamichi Goto |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-08-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC5559071?pdf=render |
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