Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry
The objective of this study was to examine exposure to estrogenic chemicals (ECs) via capsule coffee. Twenty-two brands of capsule coffee and 15 brands of French press coffee for comparison were brewed, and their contents of ECs were identified and quantified using ultra-performance liquid chromatog...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-01-01
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| Series: | Toxicology Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214750020303772 |
| _version_ | 1818383845122113536 |
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| author | Junichi R. Sakaki Melissa M. Melough Anthony A. Provatas Christopher Perkins Ock K. Chun |
| author_facet | Junichi R. Sakaki Melissa M. Melough Anthony A. Provatas Christopher Perkins Ock K. Chun |
| author_sort | Junichi R. Sakaki |
| collection | DOAJ |
| description | The objective of this study was to examine exposure to estrogenic chemicals (ECs) via capsule coffee. Twenty-two brands of capsule coffee and 15 brands of French press coffee for comparison were brewed, and their contents of ECs were identified and quantified using ultra-performance liquid chromatography with tandem mass spectrometry. Exposure to ECs in coffee were compared to tolerable daily intake guidelines to assess potential hazard to health. Benzophenone was the most frequently detected EC in capsule coffee (mean concentration ± SD: 20.37 ± 47.07 ng/mL, n = 6), followed by bisphenol A (BPA, 0.31 ± 0.71, n = 4), dibutyl phthalate (1.41 ± 3.58, n = 3), 4-nonylphenol (0.67 ± 1.82, n = 3) and bisphenol F (BPF, 0.49 ± 1.54, n = 2). BPA and BPF were each detected in 3 French press coffee samples (0.29 ± 0.58 and 0.85 ± 1.75 ng/mL, respectively). Two French press coffee brands purchased as ground coffee rather than whole bean were positive for ECs (BPA in one and BPF in both). Hazard indexes were below 1.0 for each EC for both coffee types. These results indicate that there is EC contamination in capsule and French press coffee, but the quantities of ECs are low relative to established safety guidelines. |
| first_indexed | 2024-12-14T03:12:50Z |
| format | Article |
| id | doaj.art-361c4d4088034544b57044d5f6ab9d94 |
| institution | Directory Open Access Journal |
| issn | 2214-7500 |
| language | English |
| last_indexed | 2024-12-14T03:12:50Z |
| publishDate | 2020-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Toxicology Reports |
| spelling | doaj.art-361c4d4088034544b57044d5f6ab9d942022-12-21T23:19:14ZengElsevierToxicology Reports2214-75002020-01-01710201024Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometryJunichi R. Sakaki0Melissa M. Melough1Anthony A. Provatas2Christopher Perkins3Ock K. Chun4Department of Nutritional Sciences, University of Connecticut, 27 Manter Rd., Unit 4017, Storrs, CT 06269, USADepartment of Nutritional Sciences, University of Connecticut, 27 Manter Rd., Unit 4017, Storrs, CT 06269, USACenter for Environmental Sciences and Engineering, University of Connecticut, 3107 Horsebarn Hill Rd., Storrs, CT 06269, USACenter for Environmental Sciences and Engineering, University of Connecticut, 3107 Horsebarn Hill Rd., Storrs, CT 06269, USADepartment of Nutritional Sciences, University of Connecticut, 27 Manter Rd., Unit 4017, Storrs, CT 06269, USA; Corresponding author.The objective of this study was to examine exposure to estrogenic chemicals (ECs) via capsule coffee. Twenty-two brands of capsule coffee and 15 brands of French press coffee for comparison were brewed, and their contents of ECs were identified and quantified using ultra-performance liquid chromatography with tandem mass spectrometry. Exposure to ECs in coffee were compared to tolerable daily intake guidelines to assess potential hazard to health. Benzophenone was the most frequently detected EC in capsule coffee (mean concentration ± SD: 20.37 ± 47.07 ng/mL, n = 6), followed by bisphenol A (BPA, 0.31 ± 0.71, n = 4), dibutyl phthalate (1.41 ± 3.58, n = 3), 4-nonylphenol (0.67 ± 1.82, n = 3) and bisphenol F (BPF, 0.49 ± 1.54, n = 2). BPA and BPF were each detected in 3 French press coffee samples (0.29 ± 0.58 and 0.85 ± 1.75 ng/mL, respectively). Two French press coffee brands purchased as ground coffee rather than whole bean were positive for ECs (BPA in one and BPF in both). Hazard indexes were below 1.0 for each EC for both coffee types. These results indicate that there is EC contamination in capsule and French press coffee, but the quantities of ECs are low relative to established safety guidelines.http://www.sciencedirect.com/science/article/pii/S2214750020303772Estrogenic chemicalCoffeeCapsulePlasticizerPhthalateBisphenol A |
| spellingShingle | Junichi R. Sakaki Melissa M. Melough Anthony A. Provatas Christopher Perkins Ock K. Chun Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry Toxicology Reports Estrogenic chemical Coffee Capsule Plasticizer Phthalate Bisphenol A |
| title | Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry |
| title_full | Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry |
| title_fullStr | Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry |
| title_full_unstemmed | Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry |
| title_short | Evaluation of estrogenic chemicals in capsule and French press coffee using ultra-performance liquid chromatography with tandem mass spectrometry |
| title_sort | evaluation of estrogenic chemicals in capsule and french press coffee using ultra performance liquid chromatography with tandem mass spectrometry |
| topic | Estrogenic chemical Coffee Capsule Plasticizer Phthalate Bisphenol A |
| url | http://www.sciencedirect.com/science/article/pii/S2214750020303772 |
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