Differentiation of Cells Isolated from Human Femoral Heads into Functional Osteoclasts

Differentiation of Cells Isolated from Human Femoral Heads into Functional Osteoclasts

Proper formation of the skeleton during development is crucial for the mobility of humans and the maintenance of essential organs. The production of bone is regulated by osteoblasts and osteoclasts. An imbalance of these cells can lead to a decrease in bone mineral density, which leads to fractures....

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Bibliographic Details
Main Authors: Daniel R. Halloran, Brian Heubel, Connor MacMurray, Denise Root, Mark Eskander, Sean P. McTague, Heather Pelkey, Anja Nohe
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Journal of Developmental Biology
Subjects:
bone
osteoclasts
TRAP
Cathepsin K
RAW 264.7 cells
osteoarthritis
Online Access:https://www.mdpi.com/2221-3759/10/1/6

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