Pulmonary Thromboembolism in COVID-19: a Cohort Analysis from a Tertiary Hospital in Chile/ Detección de tromboembolismo pulmonar en pacientes con COVID-19: descripción de una cohorte en un hospital terciario chileno
Introduction: The risk of pulmonary thromboembolism (PTE) in hospitalized patients is well known, but SARS-COV-2 (COVID-19) pandemic has increased its incidence, with varying evidence describing a prevalence of PTE of 3-8%. Methodology: Description of non-concurrent longitudinal cohort of hospi...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Respirar
2023-12-01
|
| Series: | Respirar |
| Subjects: | |
| Online Access: | https://respirar.alatorax.org/index.php/respirar/article/view/180/149 |
| _version_ | 1827589485647364096 |
|---|---|
| author | Andres Giglio Jimenez Rodrigo Naser Abarzua José Del Campo Peirano Patricio Astudillo Paredes Francisca García Hoffmann Isabel Hoffmann Weinberg |
| author_facet | Andres Giglio Jimenez Rodrigo Naser Abarzua José Del Campo Peirano Patricio Astudillo Paredes Francisca García Hoffmann Isabel Hoffmann Weinberg |
| author_sort | Andres Giglio Jimenez |
| collection | DOAJ |
| description | Introduction: The risk of pulmonary thromboembolism (PTE) in hospitalized patients is well known, but SARS-COV-2 (COVID-19) pandemic has increased its incidence, with varying evidence describing a prevalence of PTE of 3-8%.
Methodology: Description of non-concurrent longitudinal cohort of hospitalized patients for SARS-COV2 infection with PTE in a tertiary complexity hospital. Clinical and epidemiological features were analyzed.
Results: 151 patients were recruited with PTE and COVID-19 diagnosis, 3.4% of all hospitalized COVID patients. The median age was 67 years, 63% male patients, median length-of-stay (LOS) 20 days, and median time between COVID-19 to PTE diagnosis 13 days. Mortality at 30 days was PTE 17%, in-hospital mortality 23.1%. Mean PESI 107, Mean PESI of the deceased 116. Invasive mechanical ventilation prevalence was 31%.
Discussion: 3.4% incidence of PTE in the cohort is in the lower incidence described in other centers, considering that there was no systematic search strategy for PTE. The increased risk of in-hospital mortality and overall mortality is an alert on the possible clinical impact and may indicate the need for closer surveillance in this population. |
| first_indexed | 2024-03-09T00:58:20Z |
| format | Article |
| id | doaj.art-362110d8fb4e478d86a89cbc58d5155f |
| institution | Directory Open Access Journal |
| issn | 2953-3414 |
| language | English |
| last_indexed | 2024-03-09T00:58:20Z |
| publishDate | 2023-12-01 |
| publisher | Respirar |
| record_format | Article |
| series | Respirar |
| spelling | doaj.art-362110d8fb4e478d86a89cbc58d5155f2023-12-11T16:33:30ZengRespirarRespirar2953-34142023-12-01154227233https://doi.org/10.55720/respirar.15.4.2Pulmonary Thromboembolism in COVID-19: a Cohort Analysis from a Tertiary Hospital in Chile/ Detección de tromboembolismo pulmonar en pacientes con COVID-19: descripción de una cohorte en un hospital terciario chilenoAndres Giglio Jimenez0https://orcid.org/0000-0002-0533-4531Rodrigo Naser Abarzua1https://orcid.org/0009-0004-4484-1992José Del Campo Peirano2https://orcid.org/0009-0000-8581-1678Patricio Astudillo Paredes3https://orcid.org/0000-0002-2600-630XFrancisca García Hoffmann4https://orcid.org/0009-0008-1799-8280Isabel Hoffmann Weinberg5https://orcid.org/0009-0002-2080-798XClínicas las Condes, Centro de Paciente Crítico, Santiago de Chile, Chile; Universidad Finis Terrae, Programa de Medicina Intensiva, Santiago de Chile, ChileComplejo Asistencial Dr. Sótero del Río (CASR), Servicio de Medicina Interna, Santiago de Chile, ChileComplejo Asistencial Dr. Sótero del Río (CASR), Servicio de Medicina Interna, Santiago de Chile, ChilePontificia Universidad Católica de Chile, Escuela de Medicina, Departamento de Pediatría, Santiago de Chile, Chile; Facultad de Medicina Universidad del Desarrollo-Clínica Alemana de Santiago, Departamento de Urgencia general. Santiago de Chile, ChileUniversidad Finis Terrae, Medicina Interna, Santiago de Chile, ChileComplejo Asistencial Dr. Sótero del Río (CASR), Servicio de Medicina Interna, Santiago de Chile, ChileIntroduction: The risk of pulmonary thromboembolism (PTE) in hospitalized patients is well known, but SARS-COV-2 (COVID-19) pandemic has increased its incidence, with varying evidence describing a prevalence of PTE of 3-8%. Methodology: Description of non-concurrent longitudinal cohort of hospitalized patients for SARS-COV2 infection with PTE in a tertiary complexity hospital. Clinical and epidemiological features were analyzed. Results: 151 patients were recruited with PTE and COVID-19 diagnosis, 3.4% of all hospitalized COVID patients. The median age was 67 years, 63% male patients, median length-of-stay (LOS) 20 days, and median time between COVID-19 to PTE diagnosis 13 days. Mortality at 30 days was PTE 17%, in-hospital mortality 23.1%. Mean PESI 107, Mean PESI of the deceased 116. Invasive mechanical ventilation prevalence was 31%. Discussion: 3.4% incidence of PTE in the cohort is in the lower incidence described in other centers, considering that there was no systematic search strategy for PTE. The increased risk of in-hospital mortality and overall mortality is an alert on the possible clinical impact and may indicate the need for closer surveillance in this population.https://respirar.alatorax.org/index.php/respirar/article/view/180/149covid-19pulmonary embolismartificial respirationclinical epidemiology |
| spellingShingle | Andres Giglio Jimenez Rodrigo Naser Abarzua José Del Campo Peirano Patricio Astudillo Paredes Francisca García Hoffmann Isabel Hoffmann Weinberg Pulmonary Thromboembolism in COVID-19: a Cohort Analysis from a Tertiary Hospital in Chile/ Detección de tromboembolismo pulmonar en pacientes con COVID-19: descripción de una cohorte en un hospital terciario chileno Respirar covid-19 pulmonary embolism artificial respiration clinical epidemiology |
| title | Pulmonary Thromboembolism in COVID-19: a Cohort Analysis from a Tertiary Hospital in Chile/ Detección de tromboembolismo pulmonar en pacientes con COVID-19: descripción de una cohorte en un hospital terciario chileno |
| title_full | Pulmonary Thromboembolism in COVID-19: a Cohort Analysis from a Tertiary Hospital in Chile/ Detección de tromboembolismo pulmonar en pacientes con COVID-19: descripción de una cohorte en un hospital terciario chileno |
| title_fullStr | Pulmonary Thromboembolism in COVID-19: a Cohort Analysis from a Tertiary Hospital in Chile/ Detección de tromboembolismo pulmonar en pacientes con COVID-19: descripción de una cohorte en un hospital terciario chileno |
| title_full_unstemmed | Pulmonary Thromboembolism in COVID-19: a Cohort Analysis from a Tertiary Hospital in Chile/ Detección de tromboembolismo pulmonar en pacientes con COVID-19: descripción de una cohorte en un hospital terciario chileno |
| title_short | Pulmonary Thromboembolism in COVID-19: a Cohort Analysis from a Tertiary Hospital in Chile/ Detección de tromboembolismo pulmonar en pacientes con COVID-19: descripción de una cohorte en un hospital terciario chileno |
| title_sort | pulmonary thromboembolism in covid 19 a cohort analysis from a tertiary hospital in chile deteccion de tromboembolismo pulmonar en pacientes con covid 19 descripcion de una cohorte en un hospital terciario chileno |
| topic | covid-19 pulmonary embolism artificial respiration clinical epidemiology |
| url | https://respirar.alatorax.org/index.php/respirar/article/view/180/149 |
| work_keys_str_mv | AT andresgigliojimenez pulmonarythromboembolismincovid19acohortanalysisfromatertiaryhospitalinchiledetecciondetromboembolismopulmonarenpacientesconcovid19descripciondeunacohorteenunhospitalterciariochileno AT rodrigonaserabarzua pulmonarythromboembolismincovid19acohortanalysisfromatertiaryhospitalinchiledetecciondetromboembolismopulmonarenpacientesconcovid19descripciondeunacohorteenunhospitalterciariochileno AT josedelcampopeirano pulmonarythromboembolismincovid19acohortanalysisfromatertiaryhospitalinchiledetecciondetromboembolismopulmonarenpacientesconcovid19descripciondeunacohorteenunhospitalterciariochileno AT patricioastudilloparedes pulmonarythromboembolismincovid19acohortanalysisfromatertiaryhospitalinchiledetecciondetromboembolismopulmonarenpacientesconcovid19descripciondeunacohorteenunhospitalterciariochileno AT franciscagarciahoffmann pulmonarythromboembolismincovid19acohortanalysisfromatertiaryhospitalinchiledetecciondetromboembolismopulmonarenpacientesconcovid19descripciondeunacohorteenunhospitalterciariochileno AT isabelhoffmannweinberg pulmonarythromboembolismincovid19acohortanalysisfromatertiaryhospitalinchiledetecciondetromboembolismopulmonarenpacientesconcovid19descripciondeunacohorteenunhospitalterciariochileno |