EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription.

EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription.

Productive infection by herpesviruses involve the disabling of host-cell intrinsic defenses by viral encoded tegument proteins. Epstein-Barr Virus (EBV) typically establishes a non-productive, latent infection and it remains unclear how it confronts the host-cell intrinsic defenses that restrict vir...

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Bibliographic Details
Main Authors: Kevin Tsai, Nadezhda Thikmyanova, Jason A Wojcechowskyj, Henri-Jacques Delecluse, Paul M Lieberman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22102817/pdf/?tool=EBI

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