Females exhibit higher GluA2 levels and outperform males in active place avoidance despite increased amyloid plaques in TgF344-Alzheimer’s rats
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disease that is most prevalent in females. While estrogen provides neuroprotection in females, sex mediated differences in the development of AD pathology are not fully elucidated. Therefore, comparing events between sexes in early...
Main Authors: | Osama Chaudry, Kelechi Ndukwe, Lei Xie, Maria Figueiredo-Pereira, Peter Serrano, Patricia Rockwell |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-23801-w |
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