Arterial hypertension treatment effectiveness in elderly patients

Six-month indapamide therapy was highly effective in 70 % of elderly patients with Stage I-II arterial hypertension (AH). In 30 %, a combination of indapamide with lisinopril was necessary for achieving target blood pressure (BP) levels. Indapamide therapy was associated with significant reduction i...

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Main Authors: M. E. Statsenko, T. G. Shcherbakova, O. E. Sporova, S. V. Belenkova, Yu. V. Kalashnikova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2008-12-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/1641
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author M. E. Statsenko
T. G. Shcherbakova
O. E. Sporova
S. V. Belenkova
Yu. V. Kalashnikova
author_facet M. E. Statsenko
T. G. Shcherbakova
O. E. Sporova
S. V. Belenkova
Yu. V. Kalashnikova
author_sort M. E. Statsenko
collection DOAJ
description Six-month indapamide therapy was highly effective in 70 % of elderly patients with Stage I-II arterial hypertension (AH). In 30 %, a combination of indapamide with lisinopril was necessary for achieving target blood pressure (BP) levels. Indapamide therapy was associated with significant reduction in systolic and pulse BP, SBP variability, as well as with normalisation in circadian profile and morning dynamics of SBP and DBP. Twenty-four-week indapamide treatment resulted in significant reductions in left ventricular hypertrophy and aortal stiffness index, combined with nephroprotective effects. Indapamide did not affect carbohydrate, purine, and electrolyte metabolism. In elderly patients with AH, six-month indapamide therapy was linked to significant improvement in quality of life and cognitive and mnestic functioning
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spelling doaj.art-3628c74b9b0c4942ad00c7dd3785e74b2023-03-29T21:23:15Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202008-12-010627321426Arterial hypertension treatment effectiveness in elderly patientsM. E. Statsenko0T. G. Shcherbakova1O. E. Sporova2S. V. Belenkova3Yu. V. Kalashnikova4Волгоградский государственный медицинский университет; ГКБ № 3Волгоградский государственный медицинский университет; ГКБ № 3Волгоградский государственный медицинский университет; ГКБ № 3Волгоградский государственный медицинский университет; ГКБ № 3Волгоградский государственный медицинский университет; ГКБ № 3Six-month indapamide therapy was highly effective in 70 % of elderly patients with Stage I-II arterial hypertension (AH). In 30 %, a combination of indapamide with lisinopril was necessary for achieving target blood pressure (BP) levels. Indapamide therapy was associated with significant reduction in systolic and pulse BP, SBP variability, as well as with normalisation in circadian profile and morning dynamics of SBP and DBP. Twenty-four-week indapamide treatment resulted in significant reductions in left ventricular hypertrophy and aortal stiffness index, combined with nephroprotective effects. Indapamide did not affect carbohydrate, purine, and electrolyte metabolism. In elderly patients with AH, six-month indapamide therapy was linked to significant improvement in quality of life and cognitive and mnestic functioninghttps://russjcardiol.elpub.ru/jour/article/view/1641arterial hypertensiontherapyindapamideeffectivenesselderly age
spellingShingle M. E. Statsenko
T. G. Shcherbakova
O. E. Sporova
S. V. Belenkova
Yu. V. Kalashnikova
Arterial hypertension treatment effectiveness in elderly patients
Российский кардиологический журнал
arterial hypertension
therapy
indapamide
effectiveness
elderly age
title Arterial hypertension treatment effectiveness in elderly patients
title_full Arterial hypertension treatment effectiveness in elderly patients
title_fullStr Arterial hypertension treatment effectiveness in elderly patients
title_full_unstemmed Arterial hypertension treatment effectiveness in elderly patients
title_short Arterial hypertension treatment effectiveness in elderly patients
title_sort arterial hypertension treatment effectiveness in elderly patients
topic arterial hypertension
therapy
indapamide
effectiveness
elderly age
url https://russjcardiol.elpub.ru/jour/article/view/1641
work_keys_str_mv AT mestatsenko arterialhypertensiontreatmenteffectivenessinelderlypatients
AT tgshcherbakova arterialhypertensiontreatmenteffectivenessinelderlypatients
AT oesporova arterialhypertensiontreatmenteffectivenessinelderlypatients
AT svbelenkova arterialhypertensiontreatmenteffectivenessinelderlypatients
AT yuvkalashnikova arterialhypertensiontreatmenteffectivenessinelderlypatients