Influence of concentrations of CaCl2 on hemolytic activity of candida strains
Objective To investigate the influence of different concentrations of CaCl2 on the hemolytic activity of candida strains. Methods A total of 25 candida strains were selected, including 21 candida strains recovered from clinical specimens, and 4 reference strains of C. albicans (ATCC 90028) (Americ...
| Main Authors: | , , |
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| Format: | Article |
| Language: | zho |
| Published: |
Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases
2017-08-01
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| Series: | 口腔疾病防治 |
| Subjects: | |
| Online Access: | http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2017.08.004 |
| Summary: | Objective To investigate the influence of different concentrations of CaCl2 on the hemolytic activity of
candida strains. Methods A total of 25 candida strains were selected, including 21 candida strains recovered from
clinical specimens, and 4 reference strains of C. albicans (ATCC 90028) (American Type Culture Collection, Manassas,
VA, USA), C. glabrata (ATCC 90030), C. krusei (ATCC 6258), and C. tropicalis (ATCC 13803) respectively. CaCl2 was
added at concentrations of 0%, 0.5%, 1% and 2.5 g % (wt/vol). Plates were cultured at 37 ℃ in a 5% CO2 atmosphere
for 24 ⁃ 72 h, and the hemolytic index (Hi) was analyzed. Results Comparsions of the hemolytic indices among the
groups treated with 0.5% CaCl2 (Hi = 2.247 ± 0.079), 1% CaCl2 (Hi = 2.013 ± 0.092), 2.5% CaCl2 (Hi = 2.150 ± 0.066)
and the control (Hi = 2.749 ± 0.103) reached statistical significance (P < 0.001). Conclusion CaCl2 may produce a de⁃
crease activity in the hemolysis of candida species. |
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| ISSN: | 2096-1456 2096-1456 |