The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits

The present experiment was intended to test the hypoglycemiant effect of an alcoholic extract of roots or of the fruit seeds from “in vitro” regenerated Momordica charantia Linn. plants grown at USAMVB Timisoara. Diabetes was induced to domestic rabbits by administrating alloxan in dose of 80 mg/ kg...

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Main Authors: Horia Sărăndan, Dorica Botău, Iosif Ianculov, Florina Radu, Olga Rada, Doru Morar, Mihai Sărăndan, Maria Șerb, Adela Anghel
Format: Article
Language:English
Published: Agroprint Timisoara 2023-10-01
Series:Scientific Papers Animal Science and Biotechnologies
Subjects:
Online Access:https://spasb.ro/index.php/public_html/article/view/1360
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author Horia Sărăndan
Dorica Botău
Iosif Ianculov
Florina Radu
Olga Rada
Doru Morar
Mihai Sărăndan
Maria Șerb
Adela Anghel
author_facet Horia Sărăndan
Dorica Botău
Iosif Ianculov
Florina Radu
Olga Rada
Doru Morar
Mihai Sărăndan
Maria Șerb
Adela Anghel
author_sort Horia Sărăndan
collection DOAJ
description The present experiment was intended to test the hypoglycemiant effect of an alcoholic extract of roots or of the fruit seeds from “in vitro” regenerated Momordica charantia Linn. plants grown at USAMVB Timisoara. Diabetes was induced to domestic rabbits by administrating alloxan in dose of 80 mg/ kg body weight. In diabetic rabbits the glycemia decreased by 15.93% ten hours after the administration of the alcoholic extract in dose of 2 ml/kg body weight; the seeds of Momordica charantia Linn. reduced glycemia by 27.42% when administered in dose of 1.5 g/kg body weight. In alloxan recuperated rabbits, 5 hours after administration of the seeds, glycemia dropped 19.26%. The “in vitro” regenerated plants of Momordica charantia Linn. keep their hypoglycemiant effects.
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spelling doaj.art-362cae1eb70744db95f9845f5ffbf99a2024-04-10T05:42:35ZengAgroprint TimisoaraScientific Papers Animal Science and Biotechnologies1841-93642344-45762023-10-014315165161360The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic RabbitsHoria Sărăndan0Dorica Botău1Iosif Ianculov2Florina Radu3Olga Rada4Doru Morar5Mihai Sărăndan6Maria Șerb7Adela Anghel8USAMVB Timisoara, Calea Aradului 119, Timisoara, RomaniaUSAMVB Timisoara, Calea Aradului 119, Timisoara, RomaniaUSAMVB Timisoara, Calea Aradului 119, Timisoara, RomaniaUSAMVB Timisoara, Calea Aradului 119, Timisoara, RomaniaUSAMVB Timisoara, Calea Aradului 119, Timisoara, RomaniaUSAMVB Timisoara, Calea Aradului 119, Timisoara, RomaniaUSAMVB Timisoara, Calea Aradului 119, Timisoara, RomaniaUSAMVB Timisoara, Calea Aradului 119, Timisoara, RomaniaUSAMVB Timisoara, Calea Aradului 119, Timisoara, RomaniaThe present experiment was intended to test the hypoglycemiant effect of an alcoholic extract of roots or of the fruit seeds from “in vitro” regenerated Momordica charantia Linn. plants grown at USAMVB Timisoara. Diabetes was induced to domestic rabbits by administrating alloxan in dose of 80 mg/ kg body weight. In diabetic rabbits the glycemia decreased by 15.93% ten hours after the administration of the alcoholic extract in dose of 2 ml/kg body weight; the seeds of Momordica charantia Linn. reduced glycemia by 27.42% when administered in dose of 1.5 g/kg body weight. In alloxan recuperated rabbits, 5 hours after administration of the seeds, glycemia dropped 19.26%. The “in vitro” regenerated plants of Momordica charantia Linn. keep their hypoglycemiant effects.https://spasb.ro/index.php/public_html/article/view/1360alloxandiabetesglycemiamomordicarabbit
spellingShingle Horia Sărăndan
Dorica Botău
Iosif Ianculov
Florina Radu
Olga Rada
Doru Morar
Mihai Sărăndan
Maria Șerb
Adela Anghel
The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits
Scientific Papers Animal Science and Biotechnologies
alloxan
diabetes
glycemia
momordica
rabbit
title The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits
title_full The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits
title_fullStr The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits
title_full_unstemmed The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits
title_short The Hypoglicemic Effect of Momordica Charantia Linn in Normal and Alloxan Induced Diabetic Rabbits
title_sort hypoglicemic effect of momordica charantia linn in normal and alloxan induced diabetic rabbits
topic alloxan
diabetes
glycemia
momordica
rabbit
url https://spasb.ro/index.php/public_html/article/view/1360
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