Metabolic recycling of storage lipids promotes squalene biosynthesis in yeast

Metabolic recycling of storage lipids promotes squalene biosynthesis in yeast

Abstract Background Metabolic rewiring in microbes is an economical and sustainable strategy for synthesizing valuable natural terpenes. Terpenes are the largest class of nature-derived specialized metabolites, and many have valuable pharmaceutical or biological activity. Squalene, a medicinal terpe...

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Bibliographic Details
Main Authors: So-Hee Son, Jae-Eung Kim, Soo Young Moon, In-Seung Jang, Byung Jo Yu, Ju Young Lee
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Lipid droplet
Metabolic recycling
Yeast
Terpene
Squalene
Metabolic engineering
Online Access:https://doi.org/10.1186/s13068-022-02208-9

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