Detection of drug resistance mutations of hepatitis C virus in patients with failure of the treatment with direct acting antivirals

Background. The development of direct acting antivirals (DAAs) has spurred a revolution in treatment of patients with chronic hepatitis C. However, there are cases showing no response to treatment. In 5% of cases, the viral breakthrough is most likely caused by DAA resistance mutations in the hepati...

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Bibliographic Details
Main Authors: D. E. Valutite, A. V. Semenov, Yu. V. Ostankova, K. V. Kozlov, A. G. Borisov, V. D. Nazarov, A. A. Totolian
Format: Article
Language:Russian
Published: Central Research Institute for Epidemiology 2021-03-01
Series:Журнал микробиологии, эпидемиологии и иммунобиологии
Subjects:
Online Access:https://microbiol.elpub.ru/jour/article/view/984