Relationship between HIV stage and psychomotor speed neurocognitive score at a Kenyan sub-county hospital
Background: Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) is associated with cognitive impairment which affects psychomotor speed. Psychomotor slowing is a predictor of dementia and death in people living with HIV and AIDS. The purpose of this study was to assess t...
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| Format: | Article |
| Language: | English |
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AOSIS
2016-08-01
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| Series: | African Journal of Primary Health Care & Family Medicine |
| Subjects: | |
| Online Access: | https://phcfm.org/index.php/phcfm/article/view/1061 |
| _version_ | 1818188068095524864 |
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| author | Rachael N. Kinuthia Joseph M. Thigiti Benson N. Gakinya |
| author_facet | Rachael N. Kinuthia Joseph M. Thigiti Benson N. Gakinya |
| author_sort | Rachael N. Kinuthia |
| collection | DOAJ |
| description | Background: Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) is associated with cognitive impairment which affects psychomotor speed. Psychomotor slowing is a predictor of dementia and death in people living with HIV and AIDS. The purpose of this study was to assess the relationship between HIV disease stage and psychomotor speed neurocognitive score which will add to the body of knowledge required to manage patients with HIV and AIDS.
Objective: To determine the relationship between psychomotor speed neurocognitive score and the HIV disease stage in adults at initiation of care.
Setting: This study was conducted at Kangundo Sub-county hospital comprehensive care centre.
Methods: This was a cross-sectional study. All HIV seropositive patients aged 18 to 50 years recently initiated into care were studied. A pretested questionnaire was used to collect data. The World Health Organization (WHO) stage was used during data collection to classify study participants into asymptomatic and symptomatic groups. The grooved pegboard test was used to obtain psychomotor speed neurocognitive scores. Descriptive statistics were used to summarise data. Mann–Whitney U test, Spearman’s rho and multiple linear regression were employed in the analysis; p-value of 0.05 was considered significant.
Results: The WHO stage did not have a significant effect on the psychomotor speed neurocognitive score (p ≥ 0.05). The CD4 count had a significant effect on psychomotor speed neurocognitive score (p = 0.001).
Conclusions: There was a significant correlation between CD4 counts and psychomotor speed neurocognitive score. Efforts should be made to ensure that the CD4 counts of people living with HIV and AIDS do not continue to fall after initiation into care in order to preserve psychomotor function. |
| first_indexed | 2024-12-11T23:21:02Z |
| format | Article |
| id | doaj.art-362f02cf444044f18b868510bb33cbcd |
| institution | Directory Open Access Journal |
| issn | 2071-2928 2071-2936 |
| language | English |
| last_indexed | 2024-12-11T23:21:02Z |
| publishDate | 2016-08-01 |
| publisher | AOSIS |
| record_format | Article |
| series | African Journal of Primary Health Care & Family Medicine |
| spelling | doaj.art-362f02cf444044f18b868510bb33cbcd2022-12-22T00:46:20ZengAOSISAfrican Journal of Primary Health Care & Family Medicine2071-29282071-29362016-08-0181e1e810.4102/phcfm.v8i1.1061413Relationship between HIV stage and psychomotor speed neurocognitive score at a Kenyan sub-county hospitalRachael N. Kinuthia0Joseph M. Thigiti1Benson N. Gakinya2Department of Family Medicine, Moi University, Eldoret, NairobiDepartment of Family Medicine, Kenyatta University College of Health Sciences, NairobiDepartment of Mental Health, School of Medicine, Moi University, Eldoret, NairobiBackground: Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) is associated with cognitive impairment which affects psychomotor speed. Psychomotor slowing is a predictor of dementia and death in people living with HIV and AIDS. The purpose of this study was to assess the relationship between HIV disease stage and psychomotor speed neurocognitive score which will add to the body of knowledge required to manage patients with HIV and AIDS. Objective: To determine the relationship between psychomotor speed neurocognitive score and the HIV disease stage in adults at initiation of care. Setting: This study was conducted at Kangundo Sub-county hospital comprehensive care centre. Methods: This was a cross-sectional study. All HIV seropositive patients aged 18 to 50 years recently initiated into care were studied. A pretested questionnaire was used to collect data. The World Health Organization (WHO) stage was used during data collection to classify study participants into asymptomatic and symptomatic groups. The grooved pegboard test was used to obtain psychomotor speed neurocognitive scores. Descriptive statistics were used to summarise data. Mann–Whitney U test, Spearman’s rho and multiple linear regression were employed in the analysis; p-value of 0.05 was considered significant. Results: The WHO stage did not have a significant effect on the psychomotor speed neurocognitive score (p ≥ 0.05). The CD4 count had a significant effect on psychomotor speed neurocognitive score (p = 0.001). Conclusions: There was a significant correlation between CD4 counts and psychomotor speed neurocognitive score. Efforts should be made to ensure that the CD4 counts of people living with HIV and AIDS do not continue to fall after initiation into care in order to preserve psychomotor function.https://phcfm.org/index.php/phcfm/article/view/1061psychomotor speedasymptomatic or early HIVsymptomatic or late HIVgrooved pegboard testinitiation of care |
| spellingShingle | Rachael N. Kinuthia Joseph M. Thigiti Benson N. Gakinya Relationship between HIV stage and psychomotor speed neurocognitive score at a Kenyan sub-county hospital African Journal of Primary Health Care & Family Medicine psychomotor speed asymptomatic or early HIV symptomatic or late HIV grooved pegboard test initiation of care |
| title | Relationship between HIV stage and psychomotor speed neurocognitive score at a Kenyan sub-county hospital |
| title_full | Relationship between HIV stage and psychomotor speed neurocognitive score at a Kenyan sub-county hospital |
| title_fullStr | Relationship between HIV stage and psychomotor speed neurocognitive score at a Kenyan sub-county hospital |
| title_full_unstemmed | Relationship between HIV stage and psychomotor speed neurocognitive score at a Kenyan sub-county hospital |
| title_short | Relationship between HIV stage and psychomotor speed neurocognitive score at a Kenyan sub-county hospital |
| title_sort | relationship between hiv stage and psychomotor speed neurocognitive score at a kenyan sub county hospital |
| topic | psychomotor speed asymptomatic or early HIV symptomatic or late HIV grooved pegboard test initiation of care |
| url | https://phcfm.org/index.php/phcfm/article/view/1061 |
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