Comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol-LCT/MCT injection pain

BackgroundLidocaine has been used widely to prevent propofol injection pain. Various methods of administration exist, such as lidocaine premixed with propofol or lidocaine pretreatment using a tourniquet, but it is unclear which method of lidocaine administration is more effective for the prevention...

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Main Authors: Hyo Jin Byon, Kil Woo Lee, Hee Yong Shim, Jang Ho Song, Jong Kwon Jung, Young Deog Cha, Doo Ik Lee
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2014-02-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kjae-66-95.pdf
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author Hyo Jin Byon
Kil Woo Lee
Hee Yong Shim
Jang Ho Song
Jong Kwon Jung
Young Deog Cha
Doo Ik Lee
author_facet Hyo Jin Byon
Kil Woo Lee
Hee Yong Shim
Jang Ho Song
Jong Kwon Jung
Young Deog Cha
Doo Ik Lee
author_sort Hyo Jin Byon
collection DOAJ
description BackgroundLidocaine has been used widely to prevent propofol injection pain. Various methods of administration exist, such as lidocaine premixed with propofol or lidocaine pretreatment using a tourniquet, but it is unclear which method of lidocaine administration is more effective for the prevention of injection pain of propofol LCT/MCT. The purpose of this study was to compare pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine to prevent injection pain of propofol-LCT/MCT.MethodsPatients were randomly allocated into the pretreatment group (n = 117) or the premixed group (n = 117). The pretreatment group was pretreated with 2 ml of lidocaine 2%, held with a tourniquet, before propofol-LCT/MCT injection. The premixed group was injected with a premixed solution of propofol-LCT/MCT and 2 ml of lidocaine 2%. To evaluate the incidence and severity of pain, spontaneous verbal expressions of pain, movement of hand, frowning, and moaning were recorded, and the patients were asked to recall their pain with the visual analogue score (VAS) 30 minutes after awakening from anesthesia.ResultsOverall, injection pain occurred in 13.7% of the pretreatment group and 15.4% of the premixed group, without any statistical difference (P = 0.71). There was no difference in spontaneous verbal expressions of pain, movement of hand, frowning, and moaning between the two groups. The pain intensity (VAS) also showed no difference between the two groups (P = 0.49).ConclusionsPretreatment of lidocaine with a tourniquet showed no more benefit to prevent injection pain of propofol LCT/MCT compared to a premixed injection with lidocaine.
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spelling doaj.art-36333ad3399b432381128c1b831c726b2022-12-22T00:17:04ZengKorean Society of AnesthesiologistsKorean Journal of Anesthesiology2005-64192005-75632014-02-01662959810.4097/kjae.2014.66.2.957897Comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol-LCT/MCT injection painHyo Jin Byon0Kil Woo Lee1Hee Yong Shim2Jang Ho Song3Jong Kwon Jung4Young Deog Cha5Doo Ik Lee6Department of Anesthesiology and Pain Medicine, Inha University College of Medicine, Incheon, Korea.Department of Anesthesiology and Pain Medicine, Inha University College of Medicine, Incheon, Korea.Department of Anesthesiology and Pain Medicine, Inha University College of Medicine, Incheon, Korea.Department of Anesthesiology and Pain Medicine, Inha University College of Medicine, Incheon, Korea.Department of Anesthesiology and Pain Medicine, Inha University College of Medicine, Incheon, Korea.Department of Anesthesiology and Pain Medicine, Inha University College of Medicine, Incheon, Korea.Department of Anesthesiology and Pain Medicine, Inha University College of Medicine, Incheon, Korea.BackgroundLidocaine has been used widely to prevent propofol injection pain. Various methods of administration exist, such as lidocaine premixed with propofol or lidocaine pretreatment using a tourniquet, but it is unclear which method of lidocaine administration is more effective for the prevention of injection pain of propofol LCT/MCT. The purpose of this study was to compare pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine to prevent injection pain of propofol-LCT/MCT.MethodsPatients were randomly allocated into the pretreatment group (n = 117) or the premixed group (n = 117). The pretreatment group was pretreated with 2 ml of lidocaine 2%, held with a tourniquet, before propofol-LCT/MCT injection. The premixed group was injected with a premixed solution of propofol-LCT/MCT and 2 ml of lidocaine 2%. To evaluate the incidence and severity of pain, spontaneous verbal expressions of pain, movement of hand, frowning, and moaning were recorded, and the patients were asked to recall their pain with the visual analogue score (VAS) 30 minutes after awakening from anesthesia.ResultsOverall, injection pain occurred in 13.7% of the pretreatment group and 15.4% of the premixed group, without any statistical difference (P = 0.71). There was no difference in spontaneous verbal expressions of pain, movement of hand, frowning, and moaning between the two groups. The pain intensity (VAS) also showed no difference between the two groups (P = 0.49).ConclusionsPretreatment of lidocaine with a tourniquet showed no more benefit to prevent injection pain of propofol LCT/MCT compared to a premixed injection with lidocaine.http://ekja.org/upload/pdf/kjae-66-95.pdfemulsionsinjectionslidocainepainpropofoltourniquets
spellingShingle Hyo Jin Byon
Kil Woo Lee
Hee Yong Shim
Jang Ho Song
Jong Kwon Jung
Young Deog Cha
Doo Ik Lee
Comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol-LCT/MCT injection pain
Korean Journal of Anesthesiology
emulsions
injections
lidocaine
pain
propofol
tourniquets
title Comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol-LCT/MCT injection pain
title_full Comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol-LCT/MCT injection pain
title_fullStr Comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol-LCT/MCT injection pain
title_full_unstemmed Comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol-LCT/MCT injection pain
title_short Comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol-LCT/MCT injection pain
title_sort comparison of the preventive effects of pretreatment of lidocaine with a tourniquet and a premixed injection of lidocaine on propofol lct mct injection pain
topic emulsions
injections
lidocaine
pain
propofol
tourniquets
url http://ekja.org/upload/pdf/kjae-66-95.pdf
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