Primary follicular lymphoma of the prostate co-existing with grade group 5 prostatic adenocarcinoma and presenting as a PI-RADS lesion 4 on mpMRI

Primary prostatic lymphoma is an exceedingly rare entity comprising less than 0.09% of all prostatic cancers with follicular lymphoma making up only 12% as a subset. To our knowledge, primary follicular lymphoma co-existing with high grade prostatic adenocarcinoma presenting as a PI-RADS lesion 4 on...

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Main Authors: Shubhneet Bal, Oluwole Odujoko, Jacob Fiedler, Steven C. Sieber, Edward Beck, Gunjan Gupta
Format: Article
Language:English
Published: Elsevier 2024-05-01
Series:Urology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214442024000627
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author Shubhneet Bal
Oluwole Odujoko
Jacob Fiedler
Steven C. Sieber
Edward Beck
Gunjan Gupta
author_facet Shubhneet Bal
Oluwole Odujoko
Jacob Fiedler
Steven C. Sieber
Edward Beck
Gunjan Gupta
author_sort Shubhneet Bal
collection DOAJ
description Primary prostatic lymphoma is an exceedingly rare entity comprising less than 0.09% of all prostatic cancers with follicular lymphoma making up only 12% as a subset. To our knowledge, primary follicular lymphoma co-existing with high grade prostatic adenocarcinoma presenting as a PI-RADS lesion 4 on mpMRI has not been previously described. We report the case of a 73-year-old male who presented with mildly elevated PSA and lower urinary tract symptoms. Prostate needle biopsy revealed low grade follicular lymphoma juxtaposed with high grade prostatic adenocarcinoma. The patient has been treated with radiation therapy for adenocarcinoma and is under observation for lymphoma progression.
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spelling doaj.art-363a59142f654d5db315521ee166e52d2024-03-24T06:57:03ZengElsevierUrology Case Reports2214-44202024-05-0154102708Primary follicular lymphoma of the prostate co-existing with grade group 5 prostatic adenocarcinoma and presenting as a PI-RADS lesion 4 on mpMRIShubhneet Bal0Oluwole Odujoko1Jacob Fiedler2Steven C. Sieber3Edward Beck4Gunjan Gupta5Pathology & Laboratory Medicine Department, Danbury Hospital, Danbury, 06810, CT, United States; Corresponding author.Pathology & Laboratory Medicine Department, Danbury Hospital, Danbury, 06810, CT, United StatesNew York Medical College, Valhalla, 10595, NY, United StatesPathology & Laboratory Medicine Department, Danbury Hospital, Danbury, 06810, CT, United StatesSurgery Department (Urology Division), Danbury Hospital, Danbury, 06810, CT, United StatesPathology & Laboratory Medicine Department, Danbury Hospital, Danbury, 06810, CT, United StatesPrimary prostatic lymphoma is an exceedingly rare entity comprising less than 0.09% of all prostatic cancers with follicular lymphoma making up only 12% as a subset. To our knowledge, primary follicular lymphoma co-existing with high grade prostatic adenocarcinoma presenting as a PI-RADS lesion 4 on mpMRI has not been previously described. We report the case of a 73-year-old male who presented with mildly elevated PSA and lower urinary tract symptoms. Prostate needle biopsy revealed low grade follicular lymphoma juxtaposed with high grade prostatic adenocarcinoma. The patient has been treated with radiation therapy for adenocarcinoma and is under observation for lymphoma progression.http://www.sciencedirect.com/science/article/pii/S2214442024000627Primary prostatic lymphomaProstatic follicular lymphomaGrade group 5PI-RADS lesion 4 mpMRI
spellingShingle Shubhneet Bal
Oluwole Odujoko
Jacob Fiedler
Steven C. Sieber
Edward Beck
Gunjan Gupta
Primary follicular lymphoma of the prostate co-existing with grade group 5 prostatic adenocarcinoma and presenting as a PI-RADS lesion 4 on mpMRI
Urology Case Reports
Primary prostatic lymphoma
Prostatic follicular lymphoma
Grade group 5
PI-RADS lesion 4 mpMRI
title Primary follicular lymphoma of the prostate co-existing with grade group 5 prostatic adenocarcinoma and presenting as a PI-RADS lesion 4 on mpMRI
title_full Primary follicular lymphoma of the prostate co-existing with grade group 5 prostatic adenocarcinoma and presenting as a PI-RADS lesion 4 on mpMRI
title_fullStr Primary follicular lymphoma of the prostate co-existing with grade group 5 prostatic adenocarcinoma and presenting as a PI-RADS lesion 4 on mpMRI
title_full_unstemmed Primary follicular lymphoma of the prostate co-existing with grade group 5 prostatic adenocarcinoma and presenting as a PI-RADS lesion 4 on mpMRI
title_short Primary follicular lymphoma of the prostate co-existing with grade group 5 prostatic adenocarcinoma and presenting as a PI-RADS lesion 4 on mpMRI
title_sort primary follicular lymphoma of the prostate co existing with grade group 5 prostatic adenocarcinoma and presenting as a pi rads lesion 4 on mpmri
topic Primary prostatic lymphoma
Prostatic follicular lymphoma
Grade group 5
PI-RADS lesion 4 mpMRI
url http://www.sciencedirect.com/science/article/pii/S2214442024000627
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