The role of HFE genotype in macrophage phenotype
Abstract Background Iron regulation is essential for cellular energy production. Loss of cellular iron homeostasis has critical implications for both normal function and disease progression. The H63D variant of the HFE gene is the most common gene variant in Caucasians. The resulting mutant protein...
Main Authors: | Anne M. Nixon, Elizabeth Neely, Ian A. Simpson, James R. Connor |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12974-018-1057-0 |
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