Major dietary patterns in association with the grades of nonalcoholic fatty liver disease in newly diagnosed patients living in North of Iran
Background: Evidence suggests that dietary pattern is related to incidence and grades of nonalcoholic fatty liver disease (NAFLD). The aim of this study was to investigate the relationship between major dietary patterns and hepatic histologic features of newly diagnosed patients with NAFLD. Methods:...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | International Journal of Preventive Medicine |
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| Online Access: | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2022;volume=13;issue=1;spage=121;epage=121;aulast=Mansour-Ghanaei |
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| author | Fariborz Mansour-Ghanaei Marjan Mahdavi-Roshan Zahra Darabi Bahareh Seyyedin Farahnaz Joukar Arezoo Rezazadeh |
| author_facet | Fariborz Mansour-Ghanaei Marjan Mahdavi-Roshan Zahra Darabi Bahareh Seyyedin Farahnaz Joukar Arezoo Rezazadeh |
| author_sort | Fariborz Mansour-Ghanaei |
| collection | DOAJ |
| description | Background: Evidence suggests that dietary pattern is related to incidence and grades of nonalcoholic fatty liver disease (NAFLD). The aim of this study was to investigate the relationship between major dietary patterns and hepatic histologic features of newly diagnosed patients with NAFLD. Methods: This cross-sectional study included 260 newly diagnosed NAFLD patients. Hepatic fibrosis and steatosis were diagnosed using Fibroscan. Dietary information was obtained using a validated 168-item semiquantitative food frequency questionnaire. The association between dietary patterns and odds ratio of the grade of fibrosis and steatosis was examined by multinomial logistic regression. Results: The mean ± SD age participant was 46.53 ± 11.71 years. Fifty-seven percent of the participants were women. Two major dietary patterns were recognized: “Western dietary pattern” and “Mediterranean dietary pattern.” After adjustment for various confounders, adherence to the two extracted dietary patterns was not associated with odds of fibrosis and steatosis (P > 0.05). However, P was not significant. Patients in the second quartile of the Mediterranean dietary pattern had a higher risk for being in the F1 grade compared to those in the reference group in the crude and adjusted model. Conclusions: The major dietary patterns of NAFLD patients living in Gilan were not related to the severity of their disease. More precise study design such as cohort or interventional studies is suggested to reveal the strength of this study findings. |
| first_indexed | 2024-04-12T13:28:12Z |
| format | Article |
| id | doaj.art-36432cac1d9e402e9daef2d7c2b20a72 |
| institution | Directory Open Access Journal |
| issn | 2008-7802 2008-8213 |
| language | English |
| last_indexed | 2024-04-12T13:28:12Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Preventive Medicine |
| spelling | doaj.art-36432cac1d9e402e9daef2d7c2b20a722022-12-22T03:31:16ZengWolters Kluwer Medknow PublicationsInternational Journal of Preventive Medicine2008-78022008-82132022-01-0113112112110.4103/ijpvm.IJPVM_660_20Major dietary patterns in association with the grades of nonalcoholic fatty liver disease in newly diagnosed patients living in North of IranFariborz Mansour-GhanaeiMarjan Mahdavi-RoshanZahra DarabiBahareh SeyyedinFarahnaz JoukarArezoo RezazadehBackground: Evidence suggests that dietary pattern is related to incidence and grades of nonalcoholic fatty liver disease (NAFLD). The aim of this study was to investigate the relationship between major dietary patterns and hepatic histologic features of newly diagnosed patients with NAFLD. Methods: This cross-sectional study included 260 newly diagnosed NAFLD patients. Hepatic fibrosis and steatosis were diagnosed using Fibroscan. Dietary information was obtained using a validated 168-item semiquantitative food frequency questionnaire. The association between dietary patterns and odds ratio of the grade of fibrosis and steatosis was examined by multinomial logistic regression. Results: The mean ± SD age participant was 46.53 ± 11.71 years. Fifty-seven percent of the participants were women. Two major dietary patterns were recognized: “Western dietary pattern” and “Mediterranean dietary pattern.” After adjustment for various confounders, adherence to the two extracted dietary patterns was not associated with odds of fibrosis and steatosis (P > 0.05). However, P was not significant. Patients in the second quartile of the Mediterranean dietary pattern had a higher risk for being in the F1 grade compared to those in the reference group in the crude and adjusted model. Conclusions: The major dietary patterns of NAFLD patients living in Gilan were not related to the severity of their disease. More precise study design such as cohort or interventional studies is suggested to reveal the strength of this study findings.http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2022;volume=13;issue=1;spage=121;epage=121;aulast=Mansour-Ghanaeidietfatty liver [mesh]fibrosis [mesh]dietary pattern [mesh]irannonalcoholic fatty liver disease/diet therapy [mesh] |
| spellingShingle | Fariborz Mansour-Ghanaei Marjan Mahdavi-Roshan Zahra Darabi Bahareh Seyyedin Farahnaz Joukar Arezoo Rezazadeh Major dietary patterns in association with the grades of nonalcoholic fatty liver disease in newly diagnosed patients living in North of Iran International Journal of Preventive Medicine diet fatty liver [mesh] fibrosis [mesh] dietary pattern [mesh] iran nonalcoholic fatty liver disease/diet therapy [mesh] |
| title | Major dietary patterns in association with the grades of nonalcoholic fatty liver disease in newly diagnosed patients living in North of Iran |
| title_full | Major dietary patterns in association with the grades of nonalcoholic fatty liver disease in newly diagnosed patients living in North of Iran |
| title_fullStr | Major dietary patterns in association with the grades of nonalcoholic fatty liver disease in newly diagnosed patients living in North of Iran |
| title_full_unstemmed | Major dietary patterns in association with the grades of nonalcoholic fatty liver disease in newly diagnosed patients living in North of Iran |
| title_short | Major dietary patterns in association with the grades of nonalcoholic fatty liver disease in newly diagnosed patients living in North of Iran |
| title_sort | major dietary patterns in association with the grades of nonalcoholic fatty liver disease in newly diagnosed patients living in north of iran |
| topic | diet fatty liver [mesh] fibrosis [mesh] dietary pattern [mesh] iran nonalcoholic fatty liver disease/diet therapy [mesh] |
| url | http://www.ijpvmjournal.net/article.asp?issn=2008-7802;year=2022;volume=13;issue=1;spage=121;epage=121;aulast=Mansour-Ghanaei |
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