Experimental and Virtual Physicochemical and Pharmacokinetic Profiling of New Chemical Entities

Experimental and Virtual Physicochemical and Pharmacokinetic Profiling of New Chemical Entities

Physicochemical and pharmacokinetic profiling of new chemical entities (NCEs) allows the rapid identification and elimination of compounds with properties not suitable for further development as drug candidates. Among the complex panel of theoretical and experimental methods available to p...

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Bibliographic Details
Main Authors: Sophie Martel, Marc-Etienne Castella, Fania Bajot, Giorgio Ottaviani, Bruno Bard, Yveline Henchoz, Bénédicte Gross Valloton, Marianne Reist, Pierre-Alain Carrupt
Format: Article
Language:deu
Published: Swiss Chemical Society 2005-06-01
Series:CHIMIA
Subjects:
In vitro intestinal perfusion model
Pampa technique
Pharmacokinetic profiling
Physicochemical profiling
3d solvatochromic model
Online Access:https://chimia.ch/chimia/article/view/3993

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