5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-Monophosphate (AICAR), a Highly Conserved Purine Intermediate with Multiple Effects

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-Monophosphate (AICAR), a Highly Conserved Purine Intermediate with Multiple Effects

AICAR (5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate) is a natural metabolic intermediate of purine biosynthesis that is present in all organisms. In yeast, AICAR plays important regulatory roles under physiological conditions, notably through its direct interaction...

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Bibliographic Details
Main Authors: Bertrand Daignan-Fornier, Benoît Pinson
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Metabolites
Subjects:
AICAR
AMPK
metabolism
signal transduction
purine
ATIC
Online Access:http://www.mdpi.com/2218-1989/2/2/292

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