Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers
Electrospun nanofibers possess a large surface area and a three-dimensional porous network that makes them a perfect material for embedding functional nanoparticles for diverse applications. Herein, we report the trends in embedding upconversion nanoparticles (UCNPs) in polymeric nanofibers for maki...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-02-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/14/3/116 |
| _version_ | 1827306881547239424 |
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| author | Neha Dubey Sudeshna Chandra |
| author_facet | Neha Dubey Sudeshna Chandra |
| author_sort | Neha Dubey |
| collection | DOAJ |
| description | Electrospun nanofibers possess a large surface area and a three-dimensional porous network that makes them a perfect material for embedding functional nanoparticles for diverse applications. Herein, we report the trends in embedding upconversion nanoparticles (UCNPs) in polymeric nanofibers for making an advanced miniaturized (bio)analytical device. UCNPs have the benefits of several optical properties, like near-infrared excitation, anti-Stokes emission over a wide range from UV to NIR, narrow emission bands, an extended lifespan, and photostability. The luminescence of UCNPs can be regulated using different lanthanide elements and can be used for sensing and tracking physical processes in biological systems. We foresee that a UCNP-based nanofiber sensing platform will open opportunities in developing cost-effective, miniaturized, portable and user-friendly point-of-care sensing device for monitoring (bio)analytical processes. Major challenges in developing microfluidic (bio)analytical systems based on UCNPs@nanofibers have been reviewed and presented. |
| first_indexed | 2024-04-24T18:29:54Z |
| format | Article |
| id | doaj.art-36552847f44b4b0dabe8b7253454a61e |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-04-24T18:29:54Z |
| publishDate | 2024-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-36552847f44b4b0dabe8b7253454a61e2024-03-27T13:28:10ZengMDPI AGBiosensors2079-63742024-02-0114311610.3390/bios14030116Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric NanofibersNeha Dubey0Sudeshna Chandra1Department of Chemistry, Sunandan Divatia School of Science, SVKM’s NMIMS (Deemed to be) University, V.L. Mehta Road, Vile Parle (West), Mumbai 400056, IndiaHanse-Wissenschaftskolleg—Institute for Advanced Study (HWK), Lehmkuhlenbusch 4, 27753 Delmenhorst, GermanyElectrospun nanofibers possess a large surface area and a three-dimensional porous network that makes them a perfect material for embedding functional nanoparticles for diverse applications. Herein, we report the trends in embedding upconversion nanoparticles (UCNPs) in polymeric nanofibers for making an advanced miniaturized (bio)analytical device. UCNPs have the benefits of several optical properties, like near-infrared excitation, anti-Stokes emission over a wide range from UV to NIR, narrow emission bands, an extended lifespan, and photostability. The luminescence of UCNPs can be regulated using different lanthanide elements and can be used for sensing and tracking physical processes in biological systems. We foresee that a UCNP-based nanofiber sensing platform will open opportunities in developing cost-effective, miniaturized, portable and user-friendly point-of-care sensing device for monitoring (bio)analytical processes. Major challenges in developing microfluidic (bio)analytical systems based on UCNPs@nanofibers have been reviewed and presented.https://www.mdpi.com/2079-6374/14/3/116upconversion nanoparticlespolymeric nanofibersbiosensorsupconversion luminescencelanthanides |
| spellingShingle | Neha Dubey Sudeshna Chandra Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers Biosensors upconversion nanoparticles polymeric nanofibers biosensors upconversion luminescence lanthanides |
| title | Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers |
| title_full | Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers |
| title_fullStr | Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers |
| title_full_unstemmed | Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers |
| title_short | Miniaturized Biosensors Based on Lanthanide-Doped Upconversion Polymeric Nanofibers |
| title_sort | miniaturized biosensors based on lanthanide doped upconversion polymeric nanofibers |
| topic | upconversion nanoparticles polymeric nanofibers biosensors upconversion luminescence lanthanides |
| url | https://www.mdpi.com/2079-6374/14/3/116 |
| work_keys_str_mv | AT nehadubey miniaturizedbiosensorsbasedonlanthanidedopedupconversionpolymericnanofibers AT sudeshnachandra miniaturizedbiosensorsbasedonlanthanidedopedupconversionpolymericnanofibers |