Inhibition of BKCa channels protects neonatal hearts against myocardial ischemia and reperfusion injury
Abstract BKCa channels are large-conductance calcium and voltage-activated potassium channels that are heterogeneously expressed in a wide array of cells. Activation of BKCa channels present in mitochondria of adult ventricular cardiomyocytes is implicated in cardioprotection against ischemia-reperf...
Main Authors: | Shridhar Sanghvi, Kalina Szteyn, Devasena Ponnalagu, Divya Sridharan, Alexander Lam, Inderjot Hansra, Ankur Chaudhury, Uddalak Majumdar, Andrew R. Kohut, Shubha Gururaja Rao, Mahmood Khan, Vidu Garg, Harpreet Singh |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-04-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-022-00980-z |
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