Assessment of the societal cost of Taenia solium in Angónia district, Mozambique
Abstract Background The zoonotic parasite Taenia solium is endemic in Angónia district, Tete province, Mozambique, though the burden of the disease complex is unknown. Methods As part of two cross-sectional studies on human and porcine cysticercosis in the area, unique epidemiological and cost data...
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| Format: | Article |
| Language: | English |
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BMC
2018-03-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | http://link.springer.com/article/10.1186/s12879-018-3030-z |
| _version_ | 1818822290908905472 |
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| author | Chiara Trevisan Brecht Devleesschauwer Nicolas Praet Alberto Pondja Yunus Amade Assane Pierre Dorny Stig Milan Thamsborg Pascal Magnussen Maria Vang Johansen |
| author_facet | Chiara Trevisan Brecht Devleesschauwer Nicolas Praet Alberto Pondja Yunus Amade Assane Pierre Dorny Stig Milan Thamsborg Pascal Magnussen Maria Vang Johansen |
| author_sort | Chiara Trevisan |
| collection | DOAJ |
| description | Abstract Background The zoonotic parasite Taenia solium is endemic in Angónia district, Tete province, Mozambique, though the burden of the disease complex is unknown. Methods As part of two cross-sectional studies on human and porcine cysticercosis in the area, unique epidemiological and cost data were collected in Angónia district, Mozambique in 2007. These data provided the basis for the assessment of the societal cost of T. solium in the district, which estimates the impact of the disease on human and pig populations and includes both health and economic approaches in the analysis. Results Approximately 0.7% (95% Uncertainty Interval (UI), 0.4–0.9) and 0.4% (95% UI, 0.2–0.6) of the total population in the district was estimated to suffer from neurocysticercosis (NCC)-associated epilepsy and headache. The estimated average number of disability-adjusted life years (DALYs) due to NCC-associated epilepsy and headache was 6 (95% UI, 4–8) per thousand persons per year. The total annual costs due to T. solium cysticercosis were estimated at 90,000 USD (95% UI, 39,483–201,463) of which 72% (95% UI, 45–91) were costs linked to human cysticercosis and 28% (95% UI, 9.5–55) to pig production losses. The annual economic burden per NCC-associated epilepsy case in the district amounted to 33 USD (95% UI, 10–76). Conclusions In this highly endemic area of Mozambique a large number of individuals suffer from symptoms associated with NCC. Healthy years of life are lost and people are left living with disabilities. Infected pork poses a serious risk to the community and affects the economy of smallholder farmers. Cost for treatment and hospitalization of patients with NCC-associated epilepsy, and lack of productivity and inability of suffering patients to work, further hinder socioeconomic development. Feasible solutions framed within a country specific algorithm and stepwise approaches are needed to control the parasite in the country. |
| first_indexed | 2024-12-18T23:21:44Z |
| format | Article |
| id | doaj.art-36572c1048bf4fec8853a323e7484a1d |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-18T23:21:44Z |
| publishDate | 2018-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-36572c1048bf4fec8853a323e7484a1d2022-12-21T20:47:55ZengBMCBMC Infectious Diseases1471-23342018-03-0118111110.1186/s12879-018-3030-zAssessment of the societal cost of Taenia solium in Angónia district, MozambiqueChiara Trevisan0Brecht Devleesschauwer1Nicolas Praet2Alberto Pondja3Yunus Amade Assane4Pierre Dorny5Stig Milan Thamsborg6Pascal Magnussen7Maria Vang Johansen8Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of CopenhagenDepartment of Public Health and Surveillance, Scientific Institute of Public HealthDepartment of Biomedical Sciences, Institute of Tropical MedicineFaculty of Veterinary Medicine, Eduardo Mondlane UniversityDepartment of Neurology, University of PretoriaDepartment of Biomedical Sciences, Institute of Tropical MedicineDepartment of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of CopenhagenDepartment of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of CopenhagenDepartment of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of CopenhagenAbstract Background The zoonotic parasite Taenia solium is endemic in Angónia district, Tete province, Mozambique, though the burden of the disease complex is unknown. Methods As part of two cross-sectional studies on human and porcine cysticercosis in the area, unique epidemiological and cost data were collected in Angónia district, Mozambique in 2007. These data provided the basis for the assessment of the societal cost of T. solium in the district, which estimates the impact of the disease on human and pig populations and includes both health and economic approaches in the analysis. Results Approximately 0.7% (95% Uncertainty Interval (UI), 0.4–0.9) and 0.4% (95% UI, 0.2–0.6) of the total population in the district was estimated to suffer from neurocysticercosis (NCC)-associated epilepsy and headache. The estimated average number of disability-adjusted life years (DALYs) due to NCC-associated epilepsy and headache was 6 (95% UI, 4–8) per thousand persons per year. The total annual costs due to T. solium cysticercosis were estimated at 90,000 USD (95% UI, 39,483–201,463) of which 72% (95% UI, 45–91) were costs linked to human cysticercosis and 28% (95% UI, 9.5–55) to pig production losses. The annual economic burden per NCC-associated epilepsy case in the district amounted to 33 USD (95% UI, 10–76). Conclusions In this highly endemic area of Mozambique a large number of individuals suffer from symptoms associated with NCC. Healthy years of life are lost and people are left living with disabilities. Infected pork poses a serious risk to the community and affects the economy of smallholder farmers. Cost for treatment and hospitalization of patients with NCC-associated epilepsy, and lack of productivity and inability of suffering patients to work, further hinder socioeconomic development. Feasible solutions framed within a country specific algorithm and stepwise approaches are needed to control the parasite in the country.http://link.springer.com/article/10.1186/s12879-018-3030-zTaenia solium taeniosis/cysticercosisNeurocysticercosisEpilepsyMigraineTension-type headacheDisability-adjusted life years: Societal cost |
| spellingShingle | Chiara Trevisan Brecht Devleesschauwer Nicolas Praet Alberto Pondja Yunus Amade Assane Pierre Dorny Stig Milan Thamsborg Pascal Magnussen Maria Vang Johansen Assessment of the societal cost of Taenia solium in Angónia district, Mozambique BMC Infectious Diseases Taenia solium taeniosis/cysticercosis Neurocysticercosis Epilepsy Migraine Tension-type headache Disability-adjusted life years: Societal cost |
| title | Assessment of the societal cost of Taenia solium in Angónia district, Mozambique |
| title_full | Assessment of the societal cost of Taenia solium in Angónia district, Mozambique |
| title_fullStr | Assessment of the societal cost of Taenia solium in Angónia district, Mozambique |
| title_full_unstemmed | Assessment of the societal cost of Taenia solium in Angónia district, Mozambique |
| title_short | Assessment of the societal cost of Taenia solium in Angónia district, Mozambique |
| title_sort | assessment of the societal cost of taenia solium in angonia district mozambique |
| topic | Taenia solium taeniosis/cysticercosis Neurocysticercosis Epilepsy Migraine Tension-type headache Disability-adjusted life years: Societal cost |
| url | http://link.springer.com/article/10.1186/s12879-018-3030-z |
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