Sacroiliac joint asymmetry regarding inflammation and bone turnover: Assessment by FDG and NaF PET/CT

Objective(s): This study was undertaken to determine the role of computed tomography (CT)-based methodology to segment the SI joint and quantify the metabolic activity using positron emission tomography (PET). We measured tracer uptake in the right and left SI joints independently to look for differ...

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Main Authors: Abdullah Al-zaghal, Dani Yellani, Esha Kothekar, Thomas Werner, Poul Høilund-Carlsen, Abass Alavi
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2019-06-01
Series:Asia Oceania Journal of Nuclear Medicine and Biology
Subjects:
Online Access:http://aojnmb.mums.ac.ir/article_13349_68fd37a81642be285cbb0d3af2622b0a.pdf
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author Abdullah Al-zaghal
Dani Yellani
Esha Kothekar
Thomas Werner
Poul Høilund-Carlsen
Abass Alavi
author_facet Abdullah Al-zaghal
Dani Yellani
Esha Kothekar
Thomas Werner
Poul Høilund-Carlsen
Abass Alavi
author_sort Abdullah Al-zaghal
collection DOAJ
description Objective(s): This study was undertaken to determine the role of computed tomography (CT)-based methodology to segment the SI joint and quantify the metabolic activity using positron emission tomography (PET). We measured tracer uptake in the right and left SI joints independently to look for differences between the two sides. Further, we correlated tracer uptake with BMI and studied the inter-observer variation with regard to estimated tracer uptake in the SI joints. Methods: In this retrospective study, a total of 103 subjects (48 females, 55 males) from the CAMONA study database collected 2012-2016 at Odense University Hospital in Denmark were included. Mean age was 48±14.59 years, mean BMI was 26.68±4.31 kg/m2. The SI joints were segmented on fused PET/CT images using a 3D growing algorithm with adjustable upper and lower Hounsfield Units (HU) thresholds. The metabolic activities on the two sides were correlated with BMI. Results: For FDG, we found a higher average SUVmean on the right side (right: 1.3±0.33, left: 1.13±0.30; P
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spelling doaj.art-365859e639d24d90a2ca122e43314e112022-12-21T19:38:50ZengMashhad University of Medical SciencesAsia Oceania Journal of Nuclear Medicine and Biology2322-57182322-57262019-06-017210811410.22038/aojnmb.2019.40820.127513349Sacroiliac joint asymmetry regarding inflammation and bone turnover: Assessment by FDG and NaF PET/CTAbdullah Al-zaghal0Dani Yellani1Esha Kothekar2Thomas Werner3Poul Høilund-Carlsen4Abass Alavi5Department of Radiology, Hospital of the University of Pennsylvania, PA, USADepartment of Radiology, Hospital of the University of Pennsylvania, PA, USADepartment of Radiology, Hospital of the University of Pennsylvania, PA, USADepartment of Radiology, Hospital of the University of Pennsylvania, PA, USADepartment of Nuclear Medicine, Odense University Hospital, Odense, Denmark Institute of Clinical Research, University of Southern Denmark, Odense, DenmarkDepartment of Radiology, Hospital of the University of Pennsylvania, PA, USAObjective(s): This study was undertaken to determine the role of computed tomography (CT)-based methodology to segment the SI joint and quantify the metabolic activity using positron emission tomography (PET). We measured tracer uptake in the right and left SI joints independently to look for differences between the two sides. Further, we correlated tracer uptake with BMI and studied the inter-observer variation with regard to estimated tracer uptake in the SI joints. Methods: In this retrospective study, a total of 103 subjects (48 females, 55 males) from the CAMONA study database collected 2012-2016 at Odense University Hospital in Denmark were included. Mean age was 48±14.59 years, mean BMI was 26.68±4.31 kg/m2. The SI joints were segmented on fused PET/CT images using a 3D growing algorithm with adjustable upper and lower Hounsfield Units (HU) thresholds. The metabolic activities on the two sides were correlated with BMI. Results: For FDG, we found a higher average SUVmean on the right side (right: 1.3±0.33, left: 1.13±0.30; Phttp://aojnmb.mums.ac.ir/article_13349_68fd37a81642be285cbb0d3af2622b0a.pdfFDGNaFSacroiliacLateralityLeg-Dominance
spellingShingle Abdullah Al-zaghal
Dani Yellani
Esha Kothekar
Thomas Werner
Poul Høilund-Carlsen
Abass Alavi
Sacroiliac joint asymmetry regarding inflammation and bone turnover: Assessment by FDG and NaF PET/CT
Asia Oceania Journal of Nuclear Medicine and Biology
FDG
NaF
Sacroiliac
Laterality
Leg-Dominance
title Sacroiliac joint asymmetry regarding inflammation and bone turnover: Assessment by FDG and NaF PET/CT
title_full Sacroiliac joint asymmetry regarding inflammation and bone turnover: Assessment by FDG and NaF PET/CT
title_fullStr Sacroiliac joint asymmetry regarding inflammation and bone turnover: Assessment by FDG and NaF PET/CT
title_full_unstemmed Sacroiliac joint asymmetry regarding inflammation and bone turnover: Assessment by FDG and NaF PET/CT
title_short Sacroiliac joint asymmetry regarding inflammation and bone turnover: Assessment by FDG and NaF PET/CT
title_sort sacroiliac joint asymmetry regarding inflammation and bone turnover assessment by fdg and naf pet ct
topic FDG
NaF
Sacroiliac
Laterality
Leg-Dominance
url http://aojnmb.mums.ac.ir/article_13349_68fd37a81642be285cbb0d3af2622b0a.pdf
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