Chromofungin Ameliorates the Progression of Colitis by Regulating Alternatively Activated Macrophages

Chromofungin Ameliorates the Progression of Colitis by Regulating Alternatively Activated Macrophages

Ulcerative colitis (UC) is characterized by a functional dysregulation of alternatively activated macrophage (AAM) and intestinal epithelial cells (IECs) homeostasis. Chromogranin-A (CHGA) secreted by neuroendocrine cells is implicated in intestinal inflammation and immune dysregulation. CHGA underg...

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Bibliographic Details
Main Authors:	Nour Eissa, Hayam Hussein, Laëtitia Kermarrec, Jasmine Grover, Marie-Hélène Et Metz-Boutigue, Charles N. Bernstein, Jean-Eric Ghia
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-09-01
Series:	Frontiers in Immunology
Subjects:	chromogranin-A gut-derived peptides oxidative stress mucosal drug action epithelial homeostasis macrophages switch
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01131/full

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