Synthesis of 2-azetidinones substituted coumarin derivative
α-Naphthol is converted into 4-methylbenzo[h]chromen-2-one by reacting with ethyl acetoacetate in the presence of bismuth trichloride which is then oxidized to 2-oxo-2H-benzo[h]chromene-4-carbaldehyde and then condensed with aromatic primary amines to give Schiff bases (3a-3d). These Schiff bases...
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| Format: | Article |
| Language: | English |
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Serbian Chemical Society
2012-01-01
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| Series: | Journal of the Serbian Chemical Society |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200045M.pdf |
| _version_ | 1819025904212377600 |
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| author | Jha Mukesh S. Mashelkar Beena U. Mashelkar Uday C. |
| author_facet | Jha Mukesh S. Mashelkar Beena U. Mashelkar Uday C. |
| author_sort | Jha Mukesh S. |
| collection | DOAJ |
| description | α-Naphthol is converted into 4-methylbenzo[h]chromen-2-one by reacting with ethyl acetoacetate in the presence of bismuth trichloride which is then oxidized to 2-oxo-2H-benzo[h]chromene-4-carbaldehyde and then condensed with aromatic primary amines to give Schiff bases (3a-3d). These Schiff bases are then reacted with acid chlorides in the presence of base in toluene to give 1, 3, 4-substituted 2-azetidinones. |
| first_indexed | 2024-12-21T05:18:05Z |
| format | Article |
| id | doaj.art-365fd7356bef48fe8ba7be1b569de1e4 |
| institution | Directory Open Access Journal |
| issn | 0352-5139 |
| language | English |
| last_indexed | 2024-12-21T05:18:05Z |
| publishDate | 2012-01-01 |
| publisher | Serbian Chemical Society |
| record_format | Article |
| series | Journal of the Serbian Chemical Society |
| spelling | doaj.art-365fd7356bef48fe8ba7be1b569de1e42022-12-21T19:14:53ZengSerbian Chemical SocietyJournal of the Serbian Chemical Society0352-51392012-01-0177101339134410.2298/JSC111024045MSynthesis of 2-azetidinones substituted coumarin derivativeJha Mukesh S.Mashelkar Beena U.Mashelkar Uday C.α-Naphthol is converted into 4-methylbenzo[h]chromen-2-one by reacting with ethyl acetoacetate in the presence of bismuth trichloride which is then oxidized to 2-oxo-2H-benzo[h]chromene-4-carbaldehyde and then condensed with aromatic primary amines to give Schiff bases (3a-3d). These Schiff bases are then reacted with acid chlorides in the presence of base in toluene to give 1, 3, 4-substituted 2-azetidinones.http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200045M.pdfα-Naphtholselenium dioxidearomatic amineacid chlorideethylacetoacetatetri-n- butylamine2-azetidinone |
| spellingShingle | Jha Mukesh S. Mashelkar Beena U. Mashelkar Uday C. Synthesis of 2-azetidinones substituted coumarin derivative Journal of the Serbian Chemical Society α-Naphthol selenium dioxide aromatic amine acid chloride ethylacetoacetate tri-n- butylamine 2-azetidinone |
| title | Synthesis of 2-azetidinones substituted coumarin derivative |
| title_full | Synthesis of 2-azetidinones substituted coumarin derivative |
| title_fullStr | Synthesis of 2-azetidinones substituted coumarin derivative |
| title_full_unstemmed | Synthesis of 2-azetidinones substituted coumarin derivative |
| title_short | Synthesis of 2-azetidinones substituted coumarin derivative |
| title_sort | synthesis of 2 azetidinones substituted coumarin derivative |
| topic | α-Naphthol selenium dioxide aromatic amine acid chloride ethylacetoacetate tri-n- butylamine 2-azetidinone |
| url | http://www.doiserbia.nb.rs/img/doi/0352-5139/2012/0352-51391200045M.pdf |
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