Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study
The primary objective was to quantify changes in vascular micro-environment in spinal metastases (SM) patients treated with stereotactic body radiotherapy (SBRT) with multi-parametric dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI). The secondary objective was to study plasma biomar...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2022-12-01
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| Series: | Radiology and Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/raon-2022-0046 |
| _version_ | 1797848494058242048 |
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| author | Vellayappan Balamurugan Cheong Dennis Singbal Salil Tey Jeremy Yang Soon Yu Nang Leong Cheng Wong Alvin Lwin Sein Hung Lee Chau Periasamy Pravin Lo Simon Kumar Naresh |
| author_facet | Vellayappan Balamurugan Cheong Dennis Singbal Salil Tey Jeremy Yang Soon Yu Nang Leong Cheng Wong Alvin Lwin Sein Hung Lee Chau Periasamy Pravin Lo Simon Kumar Naresh |
| author_sort | Vellayappan Balamurugan |
| collection | DOAJ |
| description | The primary objective was to quantify changes in vascular micro-environment in spinal metastases (SM) patients treated with stereotactic body radiotherapy (SBRT) with multi-parametric dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI). The secondary objective was to study plasma biomarkers related to endothelial apoptosis. |
| first_indexed | 2024-04-09T18:29:34Z |
| format | Article |
| id | doaj.art-36608042ac024b29b3c0a72583ddadd4 |
| institution | Directory Open Access Journal |
| issn | 1581-3207 |
| language | English |
| last_indexed | 2024-04-09T18:29:34Z |
| publishDate | 2022-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Radiology and Oncology |
| spelling | doaj.art-36608042ac024b29b3c0a72583ddadd42023-04-11T17:19:28ZengSciendoRadiology and Oncology1581-32072022-12-0156452553410.2478/raon-2022-0046Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective studyVellayappan Balamurugan0Cheong Dennis1Singbal Salil2Tey Jeremy3Yang Soon Yu4Nang Leong Cheng5Wong Alvin6Lwin Sein7Hung Lee Chau8Periasamy Pravin9Lo Simon10Kumar Naresh11Department of Radiation Oncology, National University Cancer Institute Singapore, National University Hospital, SingaporeSingaporeClinical Imaging Research Centre, National University of SingaporeSingaporeSingaporeDepartment of Diagnostic Imaging, National University Hospital, SingaporeSingaporeDepartment of Radiation Oncology, National University Cancer Institute Singapore, National University Hospital, SingaporeSingaporeDepartment of Radiation Oncology, National University Cancer Institute Singapore, National University Hospital, SingaporeSingaporeDepartment of Radiation Oncology, National University Cancer Institute Singapore, National University Hospital, SingaporeSingaporeDepartment of Haematology-Oncology, National University Cancer Institute Singapore, National University Hospital, SingaporeSingaporeDivision of Neurosurgery, Department of Surgery, National University Hospital, SingaporeSingaporeDepartment of Radiology, Tan Tock Seng Hospital, SingaporeSingaporeCentre for Life Sciences (CeLS), National University of SingaporeSingaporeSingaporeDepartment of Radiation Oncology, University of Washington, Seattle, WA, USADepartment of Orthopaedic Surgery, National University Hospital, SingaporeSingaporeThe primary objective was to quantify changes in vascular micro-environment in spinal metastases (SM) patients treated with stereotactic body radiotherapy (SBRT) with multi-parametric dynamic contrast enhanced (DCE) magnetic resonance imaging (MRI). The secondary objective was to study plasma biomarkers related to endothelial apoptosis.https://doi.org/10.2478/raon-2022-0046spine metastasesstereotactic body radiotherapydce-mriendothelial apoptosis |
| spellingShingle | Vellayappan Balamurugan Cheong Dennis Singbal Salil Tey Jeremy Yang Soon Yu Nang Leong Cheng Wong Alvin Lwin Sein Hung Lee Chau Periasamy Pravin Lo Simon Kumar Naresh Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study Radiology and Oncology spine metastases stereotactic body radiotherapy dce-mri endothelial apoptosis |
| title | Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study |
| title_full | Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study |
| title_fullStr | Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study |
| title_full_unstemmed | Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study |
| title_short | Quantifying the changes in the tumour vascular micro-environment in spinal metastases treated with stereotactic body radiotherapy - a single arm prospective study |
| title_sort | quantifying the changes in the tumour vascular micro environment in spinal metastases treated with stereotactic body radiotherapy a single arm prospective study |
| topic | spine metastases stereotactic body radiotherapy dce-mri endothelial apoptosis |
| url | https://doi.org/10.2478/raon-2022-0046 |
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