Potential biochemical markers of chronic bronchitis and bronchial asthma. Current state of the problem
The literature review, according to recent publications, systematizes modern ideas about new biochemical markers of bronchopulmonary pathology, namely chronic obstructive pulmonary disease, chronic bronchitis and bronchial asthma. Information on potential biochemical markers associated with patholog...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Russian Academy of Sciences, Siberian Branch Publishing House
2020-01-01
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| Series: | Сибирский научный медицинский журнал |
| Subjects: | |
| Online Access: | https://sibmed.elpub.ru/jour/article/view/306 |
| _version_ | 1797269585683021824 |
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| author | E. A. Kurtukov Yu. I. Ragino |
| author_facet | E. A. Kurtukov Yu. I. Ragino |
| author_sort | E. A. Kurtukov |
| collection | DOAJ |
| description | The literature review, according to recent publications, systematizes modern ideas about new biochemical markers of bronchopulmonary pathology, namely chronic obstructive pulmonary disease, chronic bronchitis and bronchial asthma. Information on potential biochemical markers associated with pathology of the bronchopulmonary system is presented: pulmonary activation regulated chemokine (chemokine ligand CCL20), surfactant proteins A and D, pentraxin-3, defensins, alpha-1 antitrypsin, Clara cell protein, interleukin-19, resistin-like molecules. For each biomolecule, its characteristic, biological properties and effects are described, as well as the results of experimental and clinical studies of its effects in bronchopulmonary pathology, the association of elevated blood levels of a biomolecule with clinical manifestations of diseases. It is concluded that today there are a considerable number of new potential biomarkers of the respiratory system diseases for early and effective diagnosis, prevention and treatment of diseases, however, the effects of some of them are either insufficiently studied or contradictory and require further research, which is actively ongoing in the whole world and in Russia. |
| first_indexed | 2024-03-08T14:33:49Z |
| format | Article |
| id | doaj.art-3660ae0b8ff7416d896c66638a615966 |
| institution | Directory Open Access Journal |
| issn | 2410-2512 2410-2520 |
| language | Russian |
| last_indexed | 2024-04-25T01:50:43Z |
| publishDate | 2020-01-01 |
| publisher | Russian Academy of Sciences, Siberian Branch Publishing House |
| record_format | Article |
| series | Сибирский научный медицинский журнал |
| spelling | doaj.art-3660ae0b8ff7416d896c66638a6159662024-03-07T18:49:58ZrusRussian Academy of Sciences, Siberian Branch Publishing HouseСибирский научный медицинский журнал2410-25122410-25202020-01-0139651310.15372/SSMJ20190601214Potential biochemical markers of chronic bronchitis and bronchial asthma. Current state of the problemE. A. Kurtukov0Yu. I. Ragino1Evgeniy Alekseevich Kurtukov 630089, Novosibirsk, Boris Bogatkov str., 175/1Research Institute of Internal and Preventive Medicine -Branch of the Institute of Cytology and Genetics of SB RASThe literature review, according to recent publications, systematizes modern ideas about new biochemical markers of bronchopulmonary pathology, namely chronic obstructive pulmonary disease, chronic bronchitis and bronchial asthma. Information on potential biochemical markers associated with pathology of the bronchopulmonary system is presented: pulmonary activation regulated chemokine (chemokine ligand CCL20), surfactant proteins A and D, pentraxin-3, defensins, alpha-1 antitrypsin, Clara cell protein, interleukin-19, resistin-like molecules. For each biomolecule, its characteristic, biological properties and effects are described, as well as the results of experimental and clinical studies of its effects in bronchopulmonary pathology, the association of elevated blood levels of a biomolecule with clinical manifestations of diseases. It is concluded that today there are a considerable number of new potential biomarkers of the respiratory system diseases for early and effective diagnosis, prevention and treatment of diseases, however, the effects of some of them are either insufficiently studied or contradictory and require further research, which is actively ongoing in the whole world and in Russia.https://sibmed.elpub.ru/jour/article/view/306chronic obstructive pulmonary diseasebronchial asthmabiochemical markerspulmonary activation regulated chemokinesurfactant protein asurfactant protein dpentraxin-3defensinalpha-1 antitrypsininterleukin-19macrophage inflammatory protein |
| spellingShingle | E. A. Kurtukov Yu. I. Ragino Potential biochemical markers of chronic bronchitis and bronchial asthma. Current state of the problem Сибирский научный медицинский журнал chronic obstructive pulmonary disease bronchial asthma biochemical markers pulmonary activation regulated chemokine surfactant protein a surfactant protein d pentraxin-3 defensin alpha-1 antitrypsin interleukin-19 macrophage inflammatory protein |
| title | Potential biochemical markers of chronic bronchitis and bronchial asthma. Current state of the problem |
| title_full | Potential biochemical markers of chronic bronchitis and bronchial asthma. Current state of the problem |
| title_fullStr | Potential biochemical markers of chronic bronchitis and bronchial asthma. Current state of the problem |
| title_full_unstemmed | Potential biochemical markers of chronic bronchitis and bronchial asthma. Current state of the problem |
| title_short | Potential biochemical markers of chronic bronchitis and bronchial asthma. Current state of the problem |
| title_sort | potential biochemical markers of chronic bronchitis and bronchial asthma current state of the problem |
| topic | chronic obstructive pulmonary disease bronchial asthma biochemical markers pulmonary activation regulated chemokine surfactant protein a surfactant protein d pentraxin-3 defensin alpha-1 antitrypsin interleukin-19 macrophage inflammatory protein |
| url | https://sibmed.elpub.ru/jour/article/view/306 |
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