Profile of infections in renal transplant recipients from India
Background: Infectious disorders are a major cause of concern in renal transplant recipients (RTRs) leading to considerable morbidity and mortality. We studied the profile and outcomes of infectious disorders in a cohort of RTR. Materials and Methods: In this prospective, observational study, we eva...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2016;volume=5;issue=3;spage=611;epage=614;aulast=Kumar |
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| author | Arun Kumar Chaturbhuj Agarwal Ashok K Hooda Ashutosh Ojha Mukesh Dhillon K. V. S. Hari Kumar |
| author_facet | Arun Kumar Chaturbhuj Agarwal Ashok K Hooda Ashutosh Ojha Mukesh Dhillon K. V. S. Hari Kumar |
| author_sort | Arun Kumar |
| collection | DOAJ |
| description | Background: Infectious disorders are a major cause of concern in renal transplant recipients (RTRs) leading to considerable morbidity and mortality. We studied the profile and outcomes of infectious disorders in a cohort of RTR. Materials and Methods: In this prospective, observational study, we evaluated all RTR who presented with the features of infection. We also included asymptomatic patients with microbiological evidence of infection. We excluded patients with acute rejection, drug toxicity, and malignancy. Descriptive statistics were used to analyze the results. Results: The study population (n = 45, 35 male and 10 female) had a mean age of 35.5 ± 10.4 years and follow-up after transplant was 2.1 ± 1.7 years. Urinary tract infection (UTI, n = 15) is the most common infection followed by tuberculosis (TB, n = 8), cytomegalovirus (n = 6), candidiasis (n = 7), and hepatitis (n = 11). Miscellaneous infections such as cryptosporidiosis and pneumocystis were seen in 10 patients. Simultaneous infections with two organisms were seen in 7 patients. Four patients succumbed to multiorgan dysfunction following sepsis, another 4 patients developed chronic graft dysfunction, while the remaining 35 RTR had a good graft function. Conclusion: Infectious complications are very common in the posttransplant period including UTI and TB. Further large scale studies are required to identify the potential risk factors leading to infections in RTR. |
| first_indexed | 2024-04-14T01:19:01Z |
| format | Article |
| id | doaj.art-3664f92d807b439daee6acd713bd7e2c |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-04-14T01:19:01Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-3664f92d807b439daee6acd713bd7e2c2022-12-22T02:20:44ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632016-01-015361161410.4103/2249-4863.197320Profile of infections in renal transplant recipients from IndiaArun KumarChaturbhuj AgarwalAshok K HoodaAshutosh OjhaMukesh DhillonK. V. S. Hari KumarBackground: Infectious disorders are a major cause of concern in renal transplant recipients (RTRs) leading to considerable morbidity and mortality. We studied the profile and outcomes of infectious disorders in a cohort of RTR. Materials and Methods: In this prospective, observational study, we evaluated all RTR who presented with the features of infection. We also included asymptomatic patients with microbiological evidence of infection. We excluded patients with acute rejection, drug toxicity, and malignancy. Descriptive statistics were used to analyze the results. Results: The study population (n = 45, 35 male and 10 female) had a mean age of 35.5 ± 10.4 years and follow-up after transplant was 2.1 ± 1.7 years. Urinary tract infection (UTI, n = 15) is the most common infection followed by tuberculosis (TB, n = 8), cytomegalovirus (n = 6), candidiasis (n = 7), and hepatitis (n = 11). Miscellaneous infections such as cryptosporidiosis and pneumocystis were seen in 10 patients. Simultaneous infections with two organisms were seen in 7 patients. Four patients succumbed to multiorgan dysfunction following sepsis, another 4 patients developed chronic graft dysfunction, while the remaining 35 RTR had a good graft function. Conclusion: Infectious complications are very common in the posttransplant period including UTI and TB. Further large scale studies are required to identify the potential risk factors leading to infections in RTR.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2016;volume=5;issue=3;spage=611;epage=614;aulast=KumarIndiainfectionsrenal transplantationtuberculosisurinary tract infection |
| spellingShingle | Arun Kumar Chaturbhuj Agarwal Ashok K Hooda Ashutosh Ojha Mukesh Dhillon K. V. S. Hari Kumar Profile of infections in renal transplant recipients from India Journal of Family Medicine and Primary Care India infections renal transplantation tuberculosis urinary tract infection |
| title | Profile of infections in renal transplant recipients from India |
| title_full | Profile of infections in renal transplant recipients from India |
| title_fullStr | Profile of infections in renal transplant recipients from India |
| title_full_unstemmed | Profile of infections in renal transplant recipients from India |
| title_short | Profile of infections in renal transplant recipients from India |
| title_sort | profile of infections in renal transplant recipients from india |
| topic | India infections renal transplantation tuberculosis urinary tract infection |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2016;volume=5;issue=3;spage=611;epage=614;aulast=Kumar |
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