Analysis of Disease Spectrum of Testicular and Adnexal Lesions in Tibetan Population of Tibet
Objective To summarize and analyze the disease spectrum of testicular and adnexal lesions in Tibetan patients in Tibet Autonomous Region. Methods The relevant data of all Tibetan patients with testicular and adnexal lesions diagnosed by pathology in Tibet Autonomous Region People's Hospital...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Editorial Office of Medical Journal of Peking Union Medical College Hospital
2022-07-01
|
| Series: | Xiehe Yixue Zazhi |
| Subjects: | |
| Online Access: | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2021-0349 |
| _version_ | 1818490471276609536 |
|---|---|
| author | LUO Hanhuan WANG Qian DA Zhen DUOBU La CIREN Quzhen HUO Zhen |
| author_facet | LUO Hanhuan WANG Qian DA Zhen DUOBU La CIREN Quzhen HUO Zhen |
| author_sort | LUO Hanhuan |
| collection | DOAJ |
| description | Objective To summarize and analyze the disease spectrum of testicular and adnexal lesions in Tibetan patients in Tibet Autonomous Region. Methods The relevant data of all Tibetan patients with testicular and adnexal lesions diagnosed by pathology in Tibet Autonomous Region People's Hospital from January 2012 to March 2021 were collected retrospectively, including age, clinical manifestations, general manifestations of diseased tissues, and diagnostic results. Results There were 317 cases of testicular and adnexal lesions diagnosed by pathology, with the mean age of (38.72±19.74) years and the clinical manifestations mainly characterized by swelling and pain in the scrotum area (88.01%, 279/317). There were 85 cases of neoplastic diseases (26.81%, 85/317), in which malignant tumors accounted for 96.47%, with an average age of (38.09±14.52) years. There were 232 cases of non-neoplastic diseases (73.19%, 232/317), with an average age of (38.94±21.36) years. The gross manifestations of the lesions were as follows: the lesions of the neoplastic disease were 2-17 cm in diameter and were nodular or lobulated, the sections were solid or cystic-solid, and bleeding or necrosis could be seen in some areas; the lesions of non-neoplastic diseases were 0.6-8 cm in diameter and were mostly cystic with smooth cystic wall, and some lesions were solid nodules. Among neoplastic diseases, the tumor types were germ cell tumors (88.24%, 75/85), lymphohematopoietic tumors (4.71%, 4/85), mesenchymal tumors (4.71%, 4/85), leyding cell tumor(1.18%, 1/85), and papillary cystadenoma of the epididymis (1.18%, 1/85). Among germ cell tumors, seminoma were mainly type (66.67%, 50/75), followed by mixed germ cell tumor (14.67%, 11/75), embryonal carcinoma (12.00%, 9/75). All 4 cases of lymphohematopoietic tumor were diffuse large B-cell lymphoma. Among non-neoplastic diseases, hydrocele accounted for 56.03% (130/232), followed by inflammatory diseases (31.03%, 72/232) and testicular dysplasia (8.62%, 20/232), testicular torsion/infarction (3.88%, 9/232) and testicular adnexal cyst (0.43%, 1/232) accounted for a lower proportion. Testicular and epididymal tuberculosis (77.78%, 56/72) was the main type of inflammatory diseases. Conclusions Testicular and adnexal lesions in Tibetan people maybe more common among middle-aged people, with a complex and diverse disease spectrum, dominated by non-neoplastic disease. Hydrocele and tuberculosis are the most common non-neoplastic diseases. About 1/4 of the lesions are neoplastic diseases, and germ cell tumors are the dominant type. |
| first_indexed | 2024-12-10T17:17:29Z |
| format | Article |
| id | doaj.art-36664da40b884cce9bf8e0ba554c556b |
| institution | Directory Open Access Journal |
| issn | 1674-9081 |
| language | zho |
| last_indexed | 2024-12-10T17:17:29Z |
| publishDate | 2022-07-01 |
| publisher | Editorial Office of Medical Journal of Peking Union Medical College Hospital |
| record_format | Article |
| series | Xiehe Yixue Zazhi |
| spelling | doaj.art-36664da40b884cce9bf8e0ba554c556b2022-12-22T01:40:04ZzhoEditorial Office of Medical Journal of Peking Union Medical College HospitalXiehe Yixue Zazhi1674-90812022-07-0113468769210.12290/xhyxzz.2021-0349Analysis of Disease Spectrum of Testicular and Adnexal Lesions in Tibetan Population of TibetLUO Hanhuan0WANG Qian1DA Zhen2DUOBU La3CIREN Quzhen4HUO Zhen5Department of Pathology, Tibet Autonomous Region People's Hospital, Lhasa 850000, ChinaDepartment of Pathology, Tibet Autonomous Region People's Hospital, Lhasa 850000, ChinaDepartment of Pathology, Tibet Autonomous Region People's Hospital, Lhasa 850000, ChinaDepartment of Pathology, Tibet Autonomous Region People's Hospital, Lhasa 850000, ChinaDepartment of Pathology, Tibet Autonomous Region People's Hospital, Lhasa 850000, ChinaDepartment of Pathology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaObjective To summarize and analyze the disease spectrum of testicular and adnexal lesions in Tibetan patients in Tibet Autonomous Region. Methods The relevant data of all Tibetan patients with testicular and adnexal lesions diagnosed by pathology in Tibet Autonomous Region People's Hospital from January 2012 to March 2021 were collected retrospectively, including age, clinical manifestations, general manifestations of diseased tissues, and diagnostic results. Results There were 317 cases of testicular and adnexal lesions diagnosed by pathology, with the mean age of (38.72±19.74) years and the clinical manifestations mainly characterized by swelling and pain in the scrotum area (88.01%, 279/317). There were 85 cases of neoplastic diseases (26.81%, 85/317), in which malignant tumors accounted for 96.47%, with an average age of (38.09±14.52) years. There were 232 cases of non-neoplastic diseases (73.19%, 232/317), with an average age of (38.94±21.36) years. The gross manifestations of the lesions were as follows: the lesions of the neoplastic disease were 2-17 cm in diameter and were nodular or lobulated, the sections were solid or cystic-solid, and bleeding or necrosis could be seen in some areas; the lesions of non-neoplastic diseases were 0.6-8 cm in diameter and were mostly cystic with smooth cystic wall, and some lesions were solid nodules. Among neoplastic diseases, the tumor types were germ cell tumors (88.24%, 75/85), lymphohematopoietic tumors (4.71%, 4/85), mesenchymal tumors (4.71%, 4/85), leyding cell tumor(1.18%, 1/85), and papillary cystadenoma of the epididymis (1.18%, 1/85). Among germ cell tumors, seminoma were mainly type (66.67%, 50/75), followed by mixed germ cell tumor (14.67%, 11/75), embryonal carcinoma (12.00%, 9/75). All 4 cases of lymphohematopoietic tumor were diffuse large B-cell lymphoma. Among non-neoplastic diseases, hydrocele accounted for 56.03% (130/232), followed by inflammatory diseases (31.03%, 72/232) and testicular dysplasia (8.62%, 20/232), testicular torsion/infarction (3.88%, 9/232) and testicular adnexal cyst (0.43%, 1/232) accounted for a lower proportion. Testicular and epididymal tuberculosis (77.78%, 56/72) was the main type of inflammatory diseases. Conclusions Testicular and adnexal lesions in Tibetan people maybe more common among middle-aged people, with a complex and diverse disease spectrum, dominated by non-neoplastic disease. Hydrocele and tuberculosis are the most common non-neoplastic diseases. About 1/4 of the lesions are neoplastic diseases, and germ cell tumors are the dominant type.https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2021-0349tibetan peopletestis and adnexagerm cell tumorhydrocelepathological |
| spellingShingle | LUO Hanhuan WANG Qian DA Zhen DUOBU La CIREN Quzhen HUO Zhen Analysis of Disease Spectrum of Testicular and Adnexal Lesions in Tibetan Population of Tibet Xiehe Yixue Zazhi tibetan people testis and adnexa germ cell tumor hydrocele pathological |
| title | Analysis of Disease Spectrum of Testicular and Adnexal Lesions in Tibetan Population of Tibet |
| title_full | Analysis of Disease Spectrum of Testicular and Adnexal Lesions in Tibetan Population of Tibet |
| title_fullStr | Analysis of Disease Spectrum of Testicular and Adnexal Lesions in Tibetan Population of Tibet |
| title_full_unstemmed | Analysis of Disease Spectrum of Testicular and Adnexal Lesions in Tibetan Population of Tibet |
| title_short | Analysis of Disease Spectrum of Testicular and Adnexal Lesions in Tibetan Population of Tibet |
| title_sort | analysis of disease spectrum of testicular and adnexal lesions in tibetan population of tibet |
| topic | tibetan people testis and adnexa germ cell tumor hydrocele pathological |
| url | https://xhyxzz.pumch.cn/en/article/doi/10.12290/xhyxzz.2021-0349 |
| work_keys_str_mv | AT luohanhuan analysisofdiseasespectrumoftesticularandadnexallesionsintibetanpopulationoftibet AT wangqian analysisofdiseasespectrumoftesticularandadnexallesionsintibetanpopulationoftibet AT dazhen analysisofdiseasespectrumoftesticularandadnexallesionsintibetanpopulationoftibet AT duobula analysisofdiseasespectrumoftesticularandadnexallesionsintibetanpopulationoftibet AT cirenquzhen analysisofdiseasespectrumoftesticularandadnexallesionsintibetanpopulationoftibet AT huozhen analysisofdiseasespectrumoftesticularandadnexallesionsintibetanpopulationoftibet |