Determinants of the daily rhythm of blood fluidity

<p>Abstract</p> <p>Background</p> <p>Numerous processes in the living body exhibit daily rhythmicity. In this study, we characterized a daily rhythm of blood fluidity and identified its determinants.</p> <p>Methods</p> <p>The subjects were nine y...

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Main Authors: Kakehashi Masayuki, Sekikawa Kiyokazu, Inamizu Tsutomu, Kimura Tatsushi, Onari Kiyoshi
Format: Article
Language:English
Published: Ubiquity Press 2009-06-01
Series:Journal of Circadian Rhythms
Online Access:http://www.jcircadianrhythms.com/content/7/1/7
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author Kakehashi Masayuki
Sekikawa Kiyokazu
Inamizu Tsutomu
Kimura Tatsushi
Onari Kiyoshi
author_facet Kakehashi Masayuki
Sekikawa Kiyokazu
Inamizu Tsutomu
Kimura Tatsushi
Onari Kiyoshi
author_sort Kakehashi Masayuki
collection DOAJ
description <p>Abstract</p> <p>Background</p> <p>Numerous processes in the living body exhibit daily rhythmicity. In this study, we characterized a daily rhythm of blood fluidity and identified its determinants.</p> <p>Methods</p> <p>The subjects were nine young males. We measured the physiological parameters and performed hematological and biochemical analyses. We repeated the measurements six times during the day at 7:30 (just after getting up and before breakfast), 10:00, 13:30 (after lunch), 16:30, 19:30 (after dinner), and 21:30. The subjects performed sedentary work all day, and the contents and time of the meals were uniform. Investigation of blood rheology was based on Kikuchi's microchannel method.</p> <p>Results</p> <p>Blood passage time varied significantly with time of day. Stepwise regression analysis was used to determine the significant factors affecting blood passage time. Body temperature, heartbeat, hematocrit, white blood cell and total cholesterol were significant determinants of blood passage time.</p> <p>Conclusion</p> <p>We confirmed that blood fluidity has a daily rhythm. In addition, we found that the determinants of blood fluidity included physiological parameters such as body temperature and heartbeat, hematological parameters such as hematocrit, and white blood cell and total cholesterol.</p>
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spelling doaj.art-366650e349d74858bf9b4f037d7a1b692022-12-21T19:51:13ZengUbiquity PressJournal of Circadian Rhythms1740-33912009-06-0171710.1186/1740-3391-7-7Determinants of the daily rhythm of blood fluidityKakehashi MasayukiSekikawa KiyokazuInamizu TsutomuKimura TatsushiOnari Kiyoshi<p>Abstract</p> <p>Background</p> <p>Numerous processes in the living body exhibit daily rhythmicity. In this study, we characterized a daily rhythm of blood fluidity and identified its determinants.</p> <p>Methods</p> <p>The subjects were nine young males. We measured the physiological parameters and performed hematological and biochemical analyses. We repeated the measurements six times during the day at 7:30 (just after getting up and before breakfast), 10:00, 13:30 (after lunch), 16:30, 19:30 (after dinner), and 21:30. The subjects performed sedentary work all day, and the contents and time of the meals were uniform. Investigation of blood rheology was based on Kikuchi's microchannel method.</p> <p>Results</p> <p>Blood passage time varied significantly with time of day. Stepwise regression analysis was used to determine the significant factors affecting blood passage time. Body temperature, heartbeat, hematocrit, white blood cell and total cholesterol were significant determinants of blood passage time.</p> <p>Conclusion</p> <p>We confirmed that blood fluidity has a daily rhythm. In addition, we found that the determinants of blood fluidity included physiological parameters such as body temperature and heartbeat, hematological parameters such as hematocrit, and white blood cell and total cholesterol.</p>http://www.jcircadianrhythms.com/content/7/1/7
spellingShingle Kakehashi Masayuki
Sekikawa Kiyokazu
Inamizu Tsutomu
Kimura Tatsushi
Onari Kiyoshi
Determinants of the daily rhythm of blood fluidity
Journal of Circadian Rhythms
title Determinants of the daily rhythm of blood fluidity
title_full Determinants of the daily rhythm of blood fluidity
title_fullStr Determinants of the daily rhythm of blood fluidity
title_full_unstemmed Determinants of the daily rhythm of blood fluidity
title_short Determinants of the daily rhythm of blood fluidity
title_sort determinants of the daily rhythm of blood fluidity
url http://www.jcircadianrhythms.com/content/7/1/7
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AT inamizutsutomu determinantsofthedailyrhythmofbloodfluidity
AT kimuratatsushi determinantsofthedailyrhythmofbloodfluidity
AT onarikiyoshi determinantsofthedailyrhythmofbloodfluidity