Biosensors in Clinical Practice: Focus on Oncohematology
Biosensors are devices that are capable of detecting specific biological analytes and converting their presence or concentration into some electrical, thermal, optical or other signal that can be easily analysed. The first biosensor was designed by Clark and Lyons in 1962 as a means of measuring glu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-05-01
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| Series: | Sensors |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1424-8220/13/5/6423 |
| _version_ | 1811183982107164672 |
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| author | Agostino Cortelezzi Nicola S. Fracchiolla Silvia Artuso |
| author_facet | Agostino Cortelezzi Nicola S. Fracchiolla Silvia Artuso |
| author_sort | Agostino Cortelezzi |
| collection | DOAJ |
| description | Biosensors are devices that are capable of detecting specific biological analytes and converting their presence or concentration into some electrical, thermal, optical or other signal that can be easily analysed. The first biosensor was designed by Clark and Lyons in 1962 as a means of measuring glucose. Since then, much progress has been made and the applications of biosensors are today potentially boundless. This review is limited to their clinical applications, particularly in the field of oncohematology. Biosensors have recently been developed in order to improve the diagnosis and treatment of patients affected by hematological malignancies, such as the biosensor for assessing the in vitro pre-treatment efficacy of cytarabine in acute myeloid leukemia, and the fluorescence resonance energy transfer-based biosensor for assessing the efficacy of imatinib in chronic myeloid leukemia. The review also considers the challenges and future perspectives of biosensors in clinical practice. |
| first_indexed | 2024-04-11T13:05:46Z |
| format | Article |
| id | doaj.art-3667de55898a4f97a361459bac89ef57 |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-11T13:05:46Z |
| publishDate | 2013-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-3667de55898a4f97a361459bac89ef572022-12-22T04:22:45ZengMDPI AGSensors1424-82202013-05-011356423644710.3390/s130506423Biosensors in Clinical Practice: Focus on OncohematologyAgostino CortelezziNicola S. FracchiollaSilvia ArtusoBiosensors are devices that are capable of detecting specific biological analytes and converting their presence or concentration into some electrical, thermal, optical or other signal that can be easily analysed. The first biosensor was designed by Clark and Lyons in 1962 as a means of measuring glucose. Since then, much progress has been made and the applications of biosensors are today potentially boundless. This review is limited to their clinical applications, particularly in the field of oncohematology. Biosensors have recently been developed in order to improve the diagnosis and treatment of patients affected by hematological malignancies, such as the biosensor for assessing the in vitro pre-treatment efficacy of cytarabine in acute myeloid leukemia, and the fluorescence resonance energy transfer-based biosensor for assessing the efficacy of imatinib in chronic myeloid leukemia. The review also considers the challenges and future perspectives of biosensors in clinical practice.http://www.mdpi.com/1424-8220/13/5/6423biosensorsleukemiaoncohematologyclinical applications |
| spellingShingle | Agostino Cortelezzi Nicola S. Fracchiolla Silvia Artuso Biosensors in Clinical Practice: Focus on Oncohematology Sensors biosensors leukemia oncohematology clinical applications |
| title | Biosensors in Clinical Practice: Focus on Oncohematology |
| title_full | Biosensors in Clinical Practice: Focus on Oncohematology |
| title_fullStr | Biosensors in Clinical Practice: Focus on Oncohematology |
| title_full_unstemmed | Biosensors in Clinical Practice: Focus on Oncohematology |
| title_short | Biosensors in Clinical Practice: Focus on Oncohematology |
| title_sort | biosensors in clinical practice focus on oncohematology |
| topic | biosensors leukemia oncohematology clinical applications |
| url | http://www.mdpi.com/1424-8220/13/5/6423 |
| work_keys_str_mv | AT agostinocortelezzi biosensorsinclinicalpracticefocusononcohematology AT nicolasfracchiolla biosensorsinclinicalpracticefocusononcohematology AT silviaartuso biosensorsinclinicalpracticefocusononcohematology |