Insulin gene polymorphisms in type 1 diabetes, Addison's disease and the polyglandular autoimmune syndrome type II

Insulin gene polymorphisms in type 1 diabetes, Addison's disease and the polyglandular autoimmune syndrome type II

<p>Abstract</p> <p>Background</p> <p>Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from β-...

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Bibliographic Details
Main Authors: Hahner Stefanie, Reisch Nicole, Penna-Martinez Marissa, Meyer Gesine, Willenberg Holger S, Kahles Heinrich, Lange Britta, Ramos-Lopez Elizabeth, Seissler Jürgen, Badenhoop Klaus
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Medical Genetics
Online Access:http://www.biomedcentral.com/1471-2350/9/65

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