PhD7Faster 2.0: predicting clones propagating faster from the Ph.D.-7 phage display library by coupling PseAAC and tripeptide composition

PhD7Faster 2.0: predicting clones propagating faster from the Ph.D.-7 phage display library by coupling PseAAC and tripeptide composition

Selection from phage display libraries empowers isolation of high-affinity ligands for various targets. However, this method also identifies propagation-related target-unrelated peptides (PrTUPs). These false positive hits appear because of their amplification advantages. In this report, we present...

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Bibliographic Details
Main Authors: Bifang He, Heng Chen, Jian Huang
Format: Article
Language:English
Published: PeerJ Inc. 2019-06-01
Series:PeerJ
Subjects:
Propagation-related TUPs
Ph.D.-7 phage display library
Predictor
Feature selection
Support vector machine
Online Access:https://peerj.com/articles/7131.pdf

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