Bioactive C21 Steroidal Glycosides from <i>Euphorbia kansui</i> Promoted HepG2 Cell Apoptosis via the Degradation of ATP1A1 and Inhibited Macrophage Polarization under Co-Cultivation

Bioactive C21 Steroidal Glycosides from <i>Euphorbia kansui</i> Promoted HepG2 Cell Apoptosis via the Degradation of ATP1A1 and Inhibited Macrophage Polarization under Co-Cultivation

<i>Euphorbia kansui</i> is clinically used for the treatment of esophageal cancer, lung cancer, cancerous melanoma, asthma, pleural disorders, ascites, and pertussis, among other conditions. In this study, 12 steroids were obtained and identified from <i>E. kansui</i>, and cy...

Full description

Bibliographic Details
Main Authors: Xiaoyi Feng, Jianchun Li, Hongmei Li, Xuanqin Chen, Dan Liu, Rongtao Li
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Molecules
Subjects:
<i>Euphorbia kansui</i>
antitumor
immunomodulatory
Na<sup>+</sup>, K<sup>+</sup>-ATPase
α1 subunit of NAK
dual antitumor activity
Online Access:https://www.mdpi.com/1420-3049/28/6/2830

Internet

https://www.mdpi.com/1420-3049/28/6/2830

Similar Items