| Summary: | A disturbing amount of people are being diagnosed with several chronic ailments, which raises the prevalence of comorbidity diseases. Comorbidity frequently emerges from a disease state's first complications. The conventional medications used to treat these comorbidities frequently have negative side effects and may be hazardous to organs that were not the medications' intended targets. As a result, the necessity to create more efficient strategies to manage these chronic illnesses emerged. Bioactive substances and functional food have been utilized for therapeutic purposes over time without experiencing any discomfort, and several studies have demonstrated the health benefits of these substances and foods. In order for a food product to serve not only as a nutritional source but also for medical and therapeutic purposes, functional food products are created by integrating bioactive substances that have been shown to be helpful in the management of specific chronic conditions. In this review, the management of common non-communicable diseases namely diabetes, hypertension, obesity and erectile dysfunction and the possible functional foods that can be used to manage them singularly and as comorbidity conditions is taken into account.
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