The E3 Ubiquitin Ligase RNF5 Facilitates SARS-CoV-2 Membrane Protein-Mediated Virion Release

The E3 Ubiquitin Ligase RNF5 Facilitates SARS-CoV-2 Membrane Protein-Mediated Virion Release

ABSTRACT As an enveloped virus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) contains a membrane protein (M) that mediates viral release from cellular membranes. However, the molecular mechanisms of SARS-CoV-2 virion release remain poorly understood. In the present study, we performe...

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Bibliographic Details
Main Authors: Zhen Yuan, Bing Hu, Hurong Xiao, Xuan Tan, Yan Li, Ke Tang, Yonghui Zhang, Kun Cai, Binbin Ding
Format: Article
Language:English
Published: American Society for Microbiology 2022-02-01
Series:mBio
Subjects:
release
ubiquitination
RNF5
SARS-CoV-2
autophagy
virus-like particles
Online Access:https://journals.asm.org/doi/10.1128/mbio.03168-21

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