Deciphering Tumour Microenvironment of Liver Cancer through Deconvolution of Bulk RNA-Seq Data with Single-Cell Atlas

Deciphering Tumour Microenvironment of Liver Cancer through Deconvolution of Bulk RNA-Seq Data with Single-Cell Atlas

Liver cancers give rise to a heavy burden on healthcare worldwide. Understanding the tumour microenvironment (TME) underpins the development of precision therapy. Single-cell RNA sequencing (scRNA-seq) technology has generated high-quality cell atlases of the TME, but its wider application faces eno...

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Bibliographic Details
Main Authors: Shaoshi Zhang, Wendi Bacon, Maikel P. Peppelenbosch, Folkert van Kemenade, Andrew Peter Stubbs
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
liver cancer
tumour microenvironment
deconvolution
Online Access:https://www.mdpi.com/2072-6694/15/1/153

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