Recurrent basal cell carcinoma with maxillary bone invasion

Background: Basal cell carcinoma (BCC) is a malignant, slow growing, and locally invasive skin tumor. Advanced and neglected BCC may invade adjacent structures. The 5-year recurrence rates of facial BCCs are 4.1% after excision and 2.5% after Mohs Micrographic Surgery (MMS). The number of BCC case...

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Main Authors: Adhimukti T. Sampurna, Eva Riani, Inge Ade Krisanti, Yayi Dwina, Kuniaki Ohara
Format: Article
Language:English
Published: Universitas Indonesia 2019-12-01
Series:JDVI (Journal of General Procedural Dermatology & Venereology Indonesia)
Subjects:
Online Access:http://www.jgenprodvi.ui.ac.id/index.php/jdvi/article/view/179
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author Adhimukti T. Sampurna
Eva Riani
Inge Ade Krisanti
Yayi Dwina
Kuniaki Ohara
author_facet Adhimukti T. Sampurna
Eva Riani
Inge Ade Krisanti
Yayi Dwina
Kuniaki Ohara
author_sort Adhimukti T. Sampurna
collection DOAJ
description Background: Basal cell carcinoma (BCC) is a malignant, slow growing, and locally invasive skin tumor. Advanced and neglected BCC may invade adjacent structures. The 5-year recurrence rates of facial BCCs are 4.1% after excision and 2.5% after Mohs Micrographic Surgery (MMS). The number of BCC cases invading the bones of the head and neck region is limited. Case Illustration: A 75-year-old male complained of bleeding and ulcer enlargement on the right cheek expanding to the right nasal ala for 1 month. The patient had a history of an enlarged and painful lenticular nodule with a hyperpigmented spot that appeared 10 years ago on the right cheek and was diagnosed as BCC. The patient was treated with a wide excision having a negative pathological margin 3 years ago. He noticed that the similar lesion reappeared at the same location 2.5 years ago. Post-operative histopathological results showed nodular infiltrative BCC and maxillary bone invasion. Discussion: Based on history taking, physical examination, and diagnostic evaluation, the diagnosis of the patient was recurrent nodular infiltrative BCC. The final histopathology confirmed that tumor cells invaded the maxillary bone. After considering the treatment options, the patient opted to proceed with radiotherapy. Conclusion: Recurrent nodular BCC with invasion to the maxillary bone is a rare and interesting case. Among 140 BCC cases that we treated with MMS in our hospital from June 2014 to September 2019, this case is the first recurrent BCC with maxillary bone invasion.
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spelling doaj.art-3678e449e05d48eda5f4ef5b0d1d9f422022-12-22T02:02:02ZengUniversitas IndonesiaJDVI (Journal of General Procedural Dermatology & Venereology Indonesia)2460-79912460-79912019-12-0141444710.19100/jdvi.v4i1.179Recurrent basal cell carcinoma with maxillary bone invasionAdhimukti T. Sampurna0 Eva Riani1Inge Ade Krisanti2Yayi Dwina3 Kuniaki Ohara4Department of Dermatology and Venereology Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, IndonesiaDepartment of Dermatology and Venereology Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, IndonesiaDepartment of Dermatology and Venereology Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, IndonesiaDepartment of Anatomical Pathology Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, IndonesiaDepartment of Dermatology and Venereology Faculty of Medicine Universitas Indonesia, Dr. Cipto Mangunkusumo National Central General Hospital, Jakarta, Indonesia. Department of Dermatology, Toranomon Hospital, JapanBackground: Basal cell carcinoma (BCC) is a malignant, slow growing, and locally invasive skin tumor. Advanced and neglected BCC may invade adjacent structures. The 5-year recurrence rates of facial BCCs are 4.1% after excision and 2.5% after Mohs Micrographic Surgery (MMS). The number of BCC cases invading the bones of the head and neck region is limited. Case Illustration: A 75-year-old male complained of bleeding and ulcer enlargement on the right cheek expanding to the right nasal ala for 1 month. The patient had a history of an enlarged and painful lenticular nodule with a hyperpigmented spot that appeared 10 years ago on the right cheek and was diagnosed as BCC. The patient was treated with a wide excision having a negative pathological margin 3 years ago. He noticed that the similar lesion reappeared at the same location 2.5 years ago. Post-operative histopathological results showed nodular infiltrative BCC and maxillary bone invasion. Discussion: Based on history taking, physical examination, and diagnostic evaluation, the diagnosis of the patient was recurrent nodular infiltrative BCC. The final histopathology confirmed that tumor cells invaded the maxillary bone. After considering the treatment options, the patient opted to proceed with radiotherapy. Conclusion: Recurrent nodular BCC with invasion to the maxillary bone is a rare and interesting case. Among 140 BCC cases that we treated with MMS in our hospital from June 2014 to September 2019, this case is the first recurrent BCC with maxillary bone invasion.http://www.jgenprodvi.ui.ac.id/index.php/jdvi/article/view/179basal cell carcinomaskin tumormmsbone invasion
spellingShingle Adhimukti T. Sampurna
Eva Riani
Inge Ade Krisanti
Yayi Dwina
Kuniaki Ohara
Recurrent basal cell carcinoma with maxillary bone invasion
JDVI (Journal of General Procedural Dermatology & Venereology Indonesia)
basal cell carcinoma
skin tumor
mms
bone invasion
title Recurrent basal cell carcinoma with maxillary bone invasion
title_full Recurrent basal cell carcinoma with maxillary bone invasion
title_fullStr Recurrent basal cell carcinoma with maxillary bone invasion
title_full_unstemmed Recurrent basal cell carcinoma with maxillary bone invasion
title_short Recurrent basal cell carcinoma with maxillary bone invasion
title_sort recurrent basal cell carcinoma with maxillary bone invasion
topic basal cell carcinoma
skin tumor
mms
bone invasion
url http://www.jgenprodvi.ui.ac.id/index.php/jdvi/article/view/179
work_keys_str_mv AT adhimuktitsampurna recurrentbasalcellcarcinomawithmaxillaryboneinvasion
AT evariani recurrentbasalcellcarcinomawithmaxillaryboneinvasion
AT ingeadekrisanti recurrentbasalcellcarcinomawithmaxillaryboneinvasion
AT yayidwina recurrentbasalcellcarcinomawithmaxillaryboneinvasion
AT kuniakiohara recurrentbasalcellcarcinomawithmaxillaryboneinvasion