Gene editing in monogenic autism spectrum disorder: animal models and gene therapies

Gene editing in monogenic autism spectrum disorder: animal models and gene therapies

Autism spectrum disorder (ASD) is a lifelong neurodevelopmental disease, and its diagnosis is dependent on behavioral manifestation, such as impaired reciprocal social interactions, stereotyped repetitive behaviors, as well as restricted interests. However, ASD etiology has eluded researchers to dat...

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Bibliographic Details
Main Authors: Na Wang, Longbao Lv, Xiaoyi Huang, Mingqin Shi, Youwu Dai, Yuanyuan Wei, Bonan Xu, Chenyang Fu, Haoyu Huang, Hongling Shi, Yun Liu, Xintian Hu, Dongdong Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
autism spectrum disorder
gene editing
animal model
pathogenesis
therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1043018/full

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