Natural antibodies are required for clearance of necrotic cells and recovery from acute liver injury

Natural antibodies are required for clearance of necrotic cells and recovery from acute liver injury

Background & Aims: Hepatocellular necrosis is common in both acute and chronic liver injury and may evolve to fibrosis and liver failure. Injury leads to accumulation of necrotic cell debris in the liver, which drives persistent inflammation and poor recovery. This study investigated the rol...

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Bibliographic Details
Main Authors:	Matheus Silvério Mattos, Sofie Vandendriessche, Sara Schuermans, Lars Feyaerts, Nadine Hövelmeyer, Ari Waisman, Pedro Elias Marques
Format:	Article
Language:	English
Published:	Elsevier 2024-04-01
Series:	JHEP Reports
Subjects:	Liver injury Natural antibodies Phagocytosis Necrotic cell debris Inflammation Drug-induced liver injury
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589555924000144

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