Comparison of Ultrasound-Guided Local Dexmedetomidine Injection vs. Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial

Background: Heel pain is commonly caused by chronic plantar fasciitis, associated with pain and activity limitation in patients. Although steroid injection is a popular method to treat this disease, it has side effects and provides short-term pain relief. The study was designed to investigate the ef...

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Main Authors: Mahshid Ghasemi, Mehrdad Taheri, Fatemeh Nazari, Artadokht Khoshooei, Alireza Amanollahi, Hadi Ali Anvari
Format: Article
Language:English
Published: Shahid Beheshti University of Medical Sciences 2023-09-01
Series:Novelty in Biomedicine
Subjects:
Online Access:https://journals.sbmu.ac.ir/nbm/article/view/41828
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author Mahshid Ghasemi
Mehrdad Taheri
Fatemeh Nazari
Artadokht Khoshooei
Alireza Amanollahi
Hadi Ali Anvari
author_facet Mahshid Ghasemi
Mehrdad Taheri
Fatemeh Nazari
Artadokht Khoshooei
Alireza Amanollahi
Hadi Ali Anvari
author_sort Mahshid Ghasemi
collection DOAJ
description Background: Heel pain is commonly caused by chronic plantar fasciitis, associated with pain and activity limitation in patients. Although steroid injection is a popular method to treat this disease, it has side effects and provides short-term pain relief. The study was designed to investigate the effects of dexmedetomidine and corticosteroid injection in treating chronic plantar fasciitis. Materials and Methods: A total of 70 participants were divided into two groups. The intervention group received a mixture of dexmedetomidine (1μg/kg) with 1 ml of lidocaine 2%. The control group received a combination of 1ml of corticosteroid (40mg triamcinolone) with 1ml of lidocaine 2%. Outcome measures were evaluated with Numerical Rating Scale (NRS) and Maryland foot score (MFS) before, one, and three months after the intervention. Results: Significant improvements in NRS and MFS were observed in both groups at 1 and 3 months of follow-up compared to baseline(P<0.001). NRS score improvement in the first month was more significant in the corticosteroid group compared to the dexmedetomidine group. However, after three months, the dexmedetomidine group experienced greater pain reduction (P=0.012) and higher functional ability (P<0.001) than the corticosteroid group. Conclusion: Local injection of dexmedetomidine provided significant and long-term effects on pain severity and physical activity. Corticosteroids caused an immediate but short‑term effect, whereas sustained improvement in the dexmedetomidine group was observed during the follow-up.
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spelling doaj.art-368777279ff34c169e9df1dade5127222023-09-05T07:21:33ZengShahid Beheshti University of Medical SciencesNovelty in Biomedicine2345-39072023-09-0111330550Comparison of Ultrasound-Guided Local Dexmedetomidine Injection vs. Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical TrialMahshid Ghasemi0Mehrdad Taheri1https://orcid.org/0000-0002-8482-5434Fatemeh Nazari2Artadokht Khoshooei3Alireza Amanollahi4https://orcid.org/0000-0003-1056-5438Hadi Ali Anvari51Department of Anesthesiology and Pain Management, Akhtar Hospital, Shahid Behesthi University of Medical Sciences, Tehran, Iran 2Department of Anesthesiology and Pain Management, Imam Hossein Hospital, Shahid Behesthi University of Medical Sciences, Tehran, Iran2Department of Anesthesiology and Pain Management, Imam Hossein Hospital, Shahid Behesthi University of Medical Sciences, Tehran, Iran3Department of Anesthesiology, Jundishapur University of Medical Sciences, Ahvaz, Iran4Department of Epidemiology, Faculty of Medicine, Shahid Behesthi University of Medical Sciences, Tehran, Iran5Department of Anesthesiology, Zahedan University of Medical Sciences, Zahedan, IranBackground: Heel pain is commonly caused by chronic plantar fasciitis, associated with pain and activity limitation in patients. Although steroid injection is a popular method to treat this disease, it has side effects and provides short-term pain relief. The study was designed to investigate the effects of dexmedetomidine and corticosteroid injection in treating chronic plantar fasciitis. Materials and Methods: A total of 70 participants were divided into two groups. The intervention group received a mixture of dexmedetomidine (1μg/kg) with 1 ml of lidocaine 2%. The control group received a combination of 1ml of corticosteroid (40mg triamcinolone) with 1ml of lidocaine 2%. Outcome measures were evaluated with Numerical Rating Scale (NRS) and Maryland foot score (MFS) before, one, and three months after the intervention. Results: Significant improvements in NRS and MFS were observed in both groups at 1 and 3 months of follow-up compared to baseline(P<0.001). NRS score improvement in the first month was more significant in the corticosteroid group compared to the dexmedetomidine group. However, after three months, the dexmedetomidine group experienced greater pain reduction (P=0.012) and higher functional ability (P<0.001) than the corticosteroid group. Conclusion: Local injection of dexmedetomidine provided significant and long-term effects on pain severity and physical activity. Corticosteroids caused an immediate but short‑term effect, whereas sustained improvement in the dexmedetomidine group was observed during the follow-up.https://journals.sbmu.ac.ir/nbm/article/view/41828plantar fasciitis; dexmedetomidine; corticosteroid; numerical rating scale; maryland foot score
spellingShingle Mahshid Ghasemi
Mehrdad Taheri
Fatemeh Nazari
Artadokht Khoshooei
Alireza Amanollahi
Hadi Ali Anvari
Comparison of Ultrasound-Guided Local Dexmedetomidine Injection vs. Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial
Novelty in Biomedicine
plantar fasciitis; dexmedetomidine; corticosteroid; numerical rating scale; maryland foot score
title Comparison of Ultrasound-Guided Local Dexmedetomidine Injection vs. Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial
title_full Comparison of Ultrasound-Guided Local Dexmedetomidine Injection vs. Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial
title_fullStr Comparison of Ultrasound-Guided Local Dexmedetomidine Injection vs. Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial
title_full_unstemmed Comparison of Ultrasound-Guided Local Dexmedetomidine Injection vs. Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial
title_short Comparison of Ultrasound-Guided Local Dexmedetomidine Injection vs. Corticosteroid Injection in the Treatment of Chronic Plantar Fasciitis: A Randomized Clinical Trial
title_sort comparison of ultrasound guided local dexmedetomidine injection vs corticosteroid injection in the treatment of chronic plantar fasciitis a randomized clinical trial
topic plantar fasciitis; dexmedetomidine; corticosteroid; numerical rating scale; maryland foot score
url https://journals.sbmu.ac.ir/nbm/article/view/41828
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