Hybrid pencil beam model based on photon characteristic line algorithm for lung radiotherapy in small fields

Hybrid pencil beam model (HPBM) based on photon characteristic line algorithm has been presented to get accurate three-dimensional (3D) dose distribution for lung radiotherapy in small fields. In the model, we introduced a scattering factor to accurately describe the transport behavior of scattered...

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Main Authors: Cui Fengjie, Gu Shaoxian, Wang Ningyu, Yin Chuou, Zhang Shengyuan, Hu Jinyou, Cai Yunzhu, Wu Zhangwen, Gou Chengjun, Wang Jun
Format: Article
Language:English
Published: De Gruyter 2022-11-01
Series:Open Physics
Subjects:
Online Access:https://doi.org/10.1515/phys-2022-0194
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author Cui Fengjie
Gu Shaoxian
Wang Ningyu
Yin Chuou
Zhang Shengyuan
Hu Jinyou
Cai Yunzhu
Wu Zhangwen
Gou Chengjun
Wang Jun
author_facet Cui Fengjie
Gu Shaoxian
Wang Ningyu
Yin Chuou
Zhang Shengyuan
Hu Jinyou
Cai Yunzhu
Wu Zhangwen
Gou Chengjun
Wang Jun
author_sort Cui Fengjie
collection DOAJ
description Hybrid pencil beam model (HPBM) based on photon characteristic line algorithm has been presented to get accurate three-dimensional (3D) dose distribution for lung radiotherapy in small fields. In the model, we introduced a scattering factor to accurately describe the transport behavior of scattered photons and secondary electrons, combined with the equivalent depth correction and the weighted density correction. The pencil beam kernels of heterogeneous lung phantoms were redefined by the scattering factor and depth dose for a reference field by photon characteristic line algorithm. Subsequently, the 3D dose distribution in lung phantoms with density of 0.1, 0.26, and 0.4 g/cm3, was calculated by the Finite-size pencil beam algorithm in five regular fields and an irregular field for 6 MV photon beam. The dose distributions obtained by the HPBM are in agreement with those obtained by the MC simulations, with a relative error of less than 3% in most of the cases. However, there are apparent discrepancies at media interfaces and lung anterior portion. Moreover, at media interfaces, relative dose errors of the two methods decrease with the increase in field size and lung density. The depth range in which relative errors is greater than 3% increases with the increase in field size at lung anterior portion. In these examples, maximum relative errors are between 5 and 29%. Nevertheless, it is shown that the HPBM based on photon characteristic line algorithm has potential research values in lung dose calculation under conditions of small fields.
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spelling doaj.art-368869ca7f1647549482aa1ef12fb9a82022-12-22T03:45:01ZengDe GruyterOpen Physics2391-54712022-11-012011142115310.1515/phys-2022-0194Hybrid pencil beam model based on photon characteristic line algorithm for lung radiotherapy in small fieldsCui Fengjie0Gu Shaoxian1Wang Ningyu2Yin Chuou3Zhang Shengyuan4Hu Jinyou5Cai Yunzhu6Wu Zhangwen7Gou Chengjun8Wang Jun9Key Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaKey Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaKey Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaKey Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaKey Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaKey Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaKey Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaKey Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaKey Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaKey Laboratory of Radiation Physics and Technology of Ministry of Education, Institute of Nuclear Science and Technology, Sichuan University, Chengdu, 610064, ChinaHybrid pencil beam model (HPBM) based on photon characteristic line algorithm has been presented to get accurate three-dimensional (3D) dose distribution for lung radiotherapy in small fields. In the model, we introduced a scattering factor to accurately describe the transport behavior of scattered photons and secondary electrons, combined with the equivalent depth correction and the weighted density correction. The pencil beam kernels of heterogeneous lung phantoms were redefined by the scattering factor and depth dose for a reference field by photon characteristic line algorithm. Subsequently, the 3D dose distribution in lung phantoms with density of 0.1, 0.26, and 0.4 g/cm3, was calculated by the Finite-size pencil beam algorithm in five regular fields and an irregular field for 6 MV photon beam. The dose distributions obtained by the HPBM are in agreement with those obtained by the MC simulations, with a relative error of less than 3% in most of the cases. However, there are apparent discrepancies at media interfaces and lung anterior portion. Moreover, at media interfaces, relative dose errors of the two methods decrease with the increase in field size and lung density. The depth range in which relative errors is greater than 3% increases with the increase in field size at lung anterior portion. In these examples, maximum relative errors are between 5 and 29%. Nevertheless, it is shown that the HPBM based on photon characteristic line algorithm has potential research values in lung dose calculation under conditions of small fields.https://doi.org/10.1515/phys-2022-0194hybrid pencil beam model based on photon characteristic line algorithmmonte carlo simulationsmall fieldslung phantom
spellingShingle Cui Fengjie
Gu Shaoxian
Wang Ningyu
Yin Chuou
Zhang Shengyuan
Hu Jinyou
Cai Yunzhu
Wu Zhangwen
Gou Chengjun
Wang Jun
Hybrid pencil beam model based on photon characteristic line algorithm for lung radiotherapy in small fields
Open Physics
hybrid pencil beam model based on photon characteristic line algorithm
monte carlo simulation
small fields
lung phantom
title Hybrid pencil beam model based on photon characteristic line algorithm for lung radiotherapy in small fields
title_full Hybrid pencil beam model based on photon characteristic line algorithm for lung radiotherapy in small fields
title_fullStr Hybrid pencil beam model based on photon characteristic line algorithm for lung radiotherapy in small fields
title_full_unstemmed Hybrid pencil beam model based on photon characteristic line algorithm for lung radiotherapy in small fields
title_short Hybrid pencil beam model based on photon characteristic line algorithm for lung radiotherapy in small fields
title_sort hybrid pencil beam model based on photon characteristic line algorithm for lung radiotherapy in small fields
topic hybrid pencil beam model based on photon characteristic line algorithm
monte carlo simulation
small fields
lung phantom
url https://doi.org/10.1515/phys-2022-0194
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