Relationships between Serotonin Transporter Binding in the Raphe Nuclei, Basal Ganglia, and Hippocampus with Clinical Symptoms in Cervical Dystonia: A [11C]DASB Positron Emission Tomography Study

Relationships between Serotonin Transporter Binding in the Raphe Nuclei, Basal Ganglia, and Hippocampus with Clinical Symptoms in Cervical Dystonia: A [11C]DASB Positron Emission Tomography Study

PurposeAlterations of the central serotonergic system have been implicated in the pathophysiology of dystonia. In this molecular imaging study, we assessed whether altered presynaptic serotonin transporter (SERT) binding contributes to the pathophysiology of cervical dystonia (CD), concerning both m...

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Main Authors: Marenka Smit, David Vállez García, Bauke M. de Jong, Evelien Zoons, Jan Booij, Rudi A. Dierckx, Antoon T. Willemsen, Erik F. de Vries, Anna L. Bartels, Marina A. Tijssen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Neurology
Subjects:
dystonia
serotonin
positron emission tomography
DASB
cervical dystonia
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2018.00088/full

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