A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer

A 45-year-old female developed neurological symptoms and elevated diastolic blood pressure while on bevacizumab (Avastin) and gemcitabine for recurrent carboplatin-resistant high-grade serous ovarian cancer. A brain MRI diagnosed our patient with posterior reversible encephalopathy syndrome. We are...

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Main Authors: Hind H. Elmalik, Shereen ElAzzazy, Khaled S. Salem, Salha Bujassoum
Format: Article
Language:English
Published: Karger Publishers 2015-07-01
Series:Case Reports in Oncology
Subjects:
Online Access:http://www.karger.com/Article/FullText/435805
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author Hind H. Elmalik
Shereen ElAzzazy
Khaled S. Salem
Salha Bujassoum
author_facet Hind H. Elmalik
Shereen ElAzzazy
Khaled S. Salem
Salha Bujassoum
author_sort Hind H. Elmalik
collection DOAJ
description A 45-year-old female developed neurological symptoms and elevated diastolic blood pressure while on bevacizumab (Avastin) and gemcitabine for recurrent carboplatin-resistant high-grade serous ovarian cancer. A brain MRI diagnosed our patient with posterior reversible encephalopathy syndrome. We are discussing her presenting symptoms in this paper as well as the management and the outcome. We emphasize the importance of keeping this rare but very serious complication in all patients receiving bevacizumab.
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spelling doaj.art-36927306404f4e9f83a0499c8921575f2022-12-22T01:23:24ZengKarger PublishersCase Reports in Oncology1662-65752015-07-018229029410.1159/000435805435805A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian CancerHind H. ElmalikShereen ElAzzazyKhaled S. SalemSalha BujassoumA 45-year-old female developed neurological symptoms and elevated diastolic blood pressure while on bevacizumab (Avastin) and gemcitabine for recurrent carboplatin-resistant high-grade serous ovarian cancer. A brain MRI diagnosed our patient with posterior reversible encephalopathy syndrome. We are discussing her presenting symptoms in this paper as well as the management and the outcome. We emphasize the importance of keeping this rare but very serious complication in all patients receiving bevacizumab.http://www.karger.com/Article/FullText/435805Posterior reversible encephalopathy syndromeBevacizumab
spellingShingle Hind H. Elmalik
Shereen ElAzzazy
Khaled S. Salem
Salha Bujassoum
A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
Case Reports in Oncology
Posterior reversible encephalopathy syndrome
Bevacizumab
title A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_full A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_fullStr A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_full_unstemmed A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_short A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_sort grave outcome of posterior reversible encephalopathy syndrome in a patient receiving avastin bevacizumab for metastatic high grade serous ovarian cancer
topic Posterior reversible encephalopathy syndrome
Bevacizumab
url http://www.karger.com/Article/FullText/435805
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