Redox Homeostasis and Metabolism in Cancer: A Complex Mechanism and Potential Targeted Therapeutics

Redox Homeostasis and Metabolism in Cancer: A Complex Mechanism and Potential Targeted Therapeutics

Reactive Oxygen Species or “ROS” encompass several molecules derived from oxygen that can oxidize other molecules and subsequently transition rapidly between species. The key roles of ROS in biological processes are cell signaling, biosynthetic processes, and host defense. In cancer cells, increased...

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Bibliographic Details
Main Authors: Alia Ghoneum, Ammar Yasser Abdulfattah, Bailey Olivia Warren, Junjun Shu, Neveen Said
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
redox systems
ROS
oxidative stress
metabolism
HIF-1α
PGC-1α
Online Access:https://www.mdpi.com/1422-0067/21/9/3100

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