Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry
Abstract Background Chronic obstructive pulmonary disease (COPD) is projected to become the third cause of mortality worldwide. COPD shares several pathophysiological mechanisms with cardiovascular disease, especially atherosclerosis. However, no definite answers are available on the prognostic role...
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-08-01
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| Series: | Respiratory Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12931-022-02128-0 |
| _version_ | 1828150535181565952 |
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| author | Giuseppe De Luca Matteo Nardin Magdy Algowhary Berat Uguz Dinaldo C. Oliveira Vladimir Ganyukov Zan Zimbakov Miha Cercek Lisette Okkels Jensen Poay Huan Loh Lucian Calmac Gerard Roura Ferrer Alexandre Quadros Marek Milewski Fortunato Scotto di Uccio Clemens von Birgelen Francesco Versaci Jurrien Ten Berg Gianni Casella Aaron Wong Sung Lung Petr Kala José Luis Díez Gil Xavier Carrillo Maurits Dirksen Victor M. Becerra-Munoz Michael Kang-yin Lee Dafsah Arifa Juzar Rodrigo de Moura Joaquim Roberto Paladino Davor Milicic Periklis Davlouros Nikola Bakraceski Filippo Zilio Luca Donazzan Adriaan Kraaijeveld Gennaro Galasso Arpad Lux Lucia Marinucci Vincenzo Guiducci Maurizio Menichelli Alessandra Scoccia Aylin Hatice Yamac Kadir Ugur Mert Xacobe Flores Rios Tomas Kovarnik Michal Kidawa Josè Moreu Vincent Flavien Enrico Fabris Iñigo Lozano Martínez-Luengas Marco Boccalatte Francisco Bosa Ojeda Carlos Arellano-Serrano Gianluca Caiazzo Giuseppe Cirrincione Hsien-Li Kao Juan Sanchis Forés Luigi Vignali Helder Pereira Stephane Manzo Santiago Ordoñez Alev Arat Özkan Bruno Scheller Heidi Lehtola Rui Teles Christos Mantis Ylitalo Antti João A. Brum Silveira Rodrigo Zoni Ivan Bessonov Stefano Savonitto George Kochiadakis Dimitrios Alexopoulos Carlos E. Uribe John Kanakakis Benjamin Faurie Gabriele Gabrielli Alejandro Gutierrez Barrios Juan Pablo Bachini Alex Rocha Frankie Chor-Cheung Tam Alfredo Rodriguez Antonia Anna Lukito Veauthyelau Saint-Joy Gustavo Pessah Andrea Tuccillo Giuliana Cortese Guido Parodi Mohamed Abed Bouraghda Elvin Kedhi Pablo Lamelas Harry Suryapranata Monica Verdoia |
| author_facet | Giuseppe De Luca Matteo Nardin Magdy Algowhary Berat Uguz Dinaldo C. Oliveira Vladimir Ganyukov Zan Zimbakov Miha Cercek Lisette Okkels Jensen Poay Huan Loh Lucian Calmac Gerard Roura Ferrer Alexandre Quadros Marek Milewski Fortunato Scotto di Uccio Clemens von Birgelen Francesco Versaci Jurrien Ten Berg Gianni Casella Aaron Wong Sung Lung Petr Kala José Luis Díez Gil Xavier Carrillo Maurits Dirksen Victor M. Becerra-Munoz Michael Kang-yin Lee Dafsah Arifa Juzar Rodrigo de Moura Joaquim Roberto Paladino Davor Milicic Periklis Davlouros Nikola Bakraceski Filippo Zilio Luca Donazzan Adriaan Kraaijeveld Gennaro Galasso Arpad Lux Lucia Marinucci Vincenzo Guiducci Maurizio Menichelli Alessandra Scoccia Aylin Hatice Yamac Kadir Ugur Mert Xacobe Flores Rios Tomas Kovarnik Michal Kidawa Josè Moreu Vincent Flavien Enrico Fabris Iñigo Lozano Martínez-Luengas Marco Boccalatte Francisco Bosa Ojeda Carlos Arellano-Serrano Gianluca Caiazzo Giuseppe Cirrincione Hsien-Li Kao Juan Sanchis Forés Luigi Vignali Helder Pereira Stephane Manzo Santiago Ordoñez Alev Arat Özkan Bruno Scheller Heidi Lehtola Rui Teles Christos Mantis Ylitalo Antti João A. Brum Silveira Rodrigo Zoni Ivan Bessonov Stefano Savonitto George Kochiadakis Dimitrios Alexopoulos Carlos E. Uribe John Kanakakis Benjamin Faurie Gabriele Gabrielli Alejandro Gutierrez Barrios Juan Pablo Bachini Alex Rocha Frankie Chor-Cheung Tam Alfredo Rodriguez Antonia Anna Lukito Veauthyelau Saint-Joy Gustavo Pessah Andrea Tuccillo Giuliana Cortese Guido Parodi Mohamed Abed Bouraghda Elvin Kedhi Pablo Lamelas Harry Suryapranata Monica Verdoia |
| author_sort | Giuseppe De Luca |
| collection | DOAJ |
| description | Abstract Background Chronic obstructive pulmonary disease (COPD) is projected to become the third cause of mortality worldwide. COPD shares several pathophysiological mechanisms with cardiovascular disease, especially atherosclerosis. However, no definite answers are available on the prognostic role of COPD in the setting of ST elevation myocardial infarction (STEMI), especially during COVID-19 pandemic, among patients undergoing primary angioplasty, that is therefore the aim of the current study. Methods In the ISACS-STEMI COVID-19 registry we included retrospectively patients with STEMI treated with primary percutaneous coronary intervention (PCI) between March and June of 2019 and 2020 from 109 high-volume primary PCI centers in 4 continents. Results A total of 15,686 patients were included in this analysis. Of them, 810 (5.2%) subjects had a COPD diagnosis. They were more often elderly and with a more pronounced cardiovascular risk profile. No preminent procedural dissimilarities were noticed except for a lower proportion of dual antiplatelet therapy at discharge among COPD patients (98.9% vs. 98.1%, P = 0.038). With regards to short-term fatal outcomes, both in-hospital and 30-days mortality occurred more frequently among COPD patients, similarly in pre-COVID-19 and COVID-19 era. However, after adjustment for main baseline differences, COPD did not result as independent predictor for in-hospital death (adjusted OR [95% CI] = 0.913[0.658–1.266], P = 0.585) nor for 30-days mortality (adjusted OR [95% CI] = 0.850 [0.620–1.164], P = 0.310). No significant differences were detected in terms of SARS-CoV-2 positivity between the two groups. Conclusion This is one of the largest studies investigating characteristics and outcome of COPD patients with STEMI undergoing primary angioplasty, especially during COVID pandemic. COPD was associated with significantly higher rates of in-hospital and 30-days mortality. However, this association disappeared after adjustment for baseline characteristics. Furthermore, COPD did not significantly affect SARS-CoV-2 positivity. Trial registration number: NCT 04412655 (2nd June 2020). |
| first_indexed | 2024-04-11T21:45:46Z |
| format | Article |
| id | doaj.art-36968b872a2448fbb2d60060d7ea0149 |
| institution | Directory Open Access Journal |
| issn | 1465-993X |
| language | English |
| last_indexed | 2024-04-11T21:45:46Z |
| publishDate | 2022-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-36968b872a2448fbb2d60060d7ea01492022-12-22T04:01:26ZengBMCRespiratory Research1465-993X2022-08-012311910.1186/s12931-022-02128-0Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registryGiuseppe De Luca0Matteo Nardin1Magdy Algowhary2Berat Uguz3Dinaldo C. Oliveira4Vladimir Ganyukov5Zan Zimbakov6Miha Cercek7Lisette Okkels Jensen8Poay Huan Loh9Lucian Calmac10Gerard Roura Ferrer11Alexandre Quadros12Marek Milewski13Fortunato Scotto di Uccio14Clemens von Birgelen15Francesco Versaci16Jurrien Ten Berg17Gianni Casella18Aaron Wong Sung Lung19Petr Kala20José Luis Díez Gil21Xavier Carrillo22Maurits Dirksen23Victor M. Becerra-Munoz24Michael Kang-yin Lee25Dafsah Arifa Juzar26Rodrigo de Moura Joaquim27Roberto Paladino28Davor Milicic29Periklis Davlouros30Nikola Bakraceski31Filippo Zilio32Luca Donazzan33Adriaan Kraaijeveld34Gennaro Galasso35Arpad Lux36Lucia Marinucci37Vincenzo Guiducci38Maurizio Menichelli39Alessandra Scoccia40Aylin Hatice Yamac41Kadir Ugur Mert42Xacobe Flores Rios43Tomas Kovarnik44Michal Kidawa45Josè Moreu46Vincent Flavien47Enrico Fabris48Iñigo Lozano Martínez-Luengas49Marco Boccalatte50Francisco Bosa Ojeda51Carlos Arellano-Serrano52Gianluca Caiazzo53Giuseppe Cirrincione54Hsien-Li Kao55Juan Sanchis Forés56Luigi Vignali57Helder Pereira58Stephane Manzo59Santiago Ordoñez60Alev Arat Özkan61Bruno Scheller62Heidi Lehtola63Rui Teles64Christos Mantis65Ylitalo Antti66João A. Brum Silveira67Rodrigo Zoni68Ivan Bessonov69Stefano Savonitto70George Kochiadakis71Dimitrios Alexopoulos72Carlos E. Uribe73John Kanakakis74Benjamin Faurie75Gabriele Gabrielli76Alejandro Gutierrez Barrios77Juan Pablo Bachini78Alex Rocha79Frankie Chor-Cheung Tam80Alfredo Rodriguez81Antonia Anna Lukito82Veauthyelau Saint-Joy83Gustavo Pessah84Andrea Tuccillo85Giuliana Cortese86Guido Parodi87Mohamed Abed Bouraghda88Elvin Kedhi89Pablo Lamelas90Harry Suryapranata91Monica Verdoia92Division of Clinical and Experimental Cardiology, AOU SassariThird Medicine Division, ASST Spedali CiviliDivision of Cardiology, Assiut University Heart Hospital, Assiut UniversityDivision of Cardiology, Bursa City HospitalPronto de Socorro Cardiologico Prof. Luis Tavares, Centro PROCAPE, Federal University of PernambucoDepartment of Heart and Vascular Surgery, State Research Institute for Complex Issues of Cardiovascular DiseasesMedical Faculty, University Clinic for Cardiology, Ss’ Cyril and Methodius UniversityCentre for Intensive Internal Medicine, University Medical CentreDivision of Cardiology, Odense Universitets HospitalDepartment of Cardiology, National University HospitalClinic Emergency Hospital of BucharestInterventional Cardiology Unit, Heart Disease Institute, Hospital Universitari de BellvitgeInstituto de Cardiologia do Rio Grande do SulDivision of Cardiology, Medical University of SileziaDivision of Cardiology, Ospedale del MareDepartment of Cardiology, Medisch Spectrum Twente, Thoraxcentrum TwenteDivision of Cardiology, Ospedale Santa Maria Goretti LatinaDivision of Cardiology, St Antonius HospitalDivision of Cardiology, Ospedale Maggiore BolognaDepartment of Cardiology, National Heart CenterUniversity Hospital Brno, Medical Faculty of Masaryk UniversityH. Universitario y Politécnico La FeHospital Germans Triasi PujolDivision of Cardiology, Northwest ClinicsHospital Clínico Universitario Virgen de la VictoriaDepartment of Cardiology, Queen Elizabeth Hospital, University of Hong KongDepartment of Cardiology and Vascular Medicine, University of Indonesia National Cardiovascular Center “Harapan Kita”Instituto de Cardiologia de Santa Catarina Praia CompridaDivision of Cardiology, Clinica Villa dei FioriDepartment of Cardiology, University Hospital Centre, University of ZagrebInvasive Cardiology and Congenital Heart Disease, Patras University HospitalCenter for Cardiovascular DiseasesDivision of Cardiology, Ospedale Santa Chiara di TrentoDivision of Cardiology, Ospedale “S. Maurizio” BolzanoDivision of Cardiology, UMC UtrechtDivision of Cardiology, Ospedale San Giovanni di Dio e Ruggi d’AragonaMaastricht University Medical CenterDivision of Cardiology, Azienda Ospedaliera “Ospedali Riuniti Marche Nord”Division of Cardiology, AUSL-IRCCS Reggio EmiliaDivision of Cardiology, Ospedale “F. Spaziani”Division of Cardiology, Ospedale “Sant’Anna”Department of Cardiology, Hospital Bezmialem Vakıf UniversityDivision of Cardiology, Faculty of Medicine, Eskisehir Osmangazi UniversityComplexo Hospetaliero Universitario La CorunaUniversity Hospital PragueCentral Hospital of Medical University of LodzDivision of Cardiology, Complejo Hospitalario de ToledoDivision of Cardiology, Center Hospitalier Universitaire de LilleAzienda Ospedaliero-Universitaria Ospedali Riuniti TriesteDivision of Cardiology, Hospital CabueñesDivision of Cardiology, Ospedale Santa Maria delle GrazieDivision of Cardiology, Hospital Universitario de CanariasDivision of Cardiology, Hospital Puerta de Hierro MajadahondaDivision of Cardiology, Ospedale “G Moscati”Division of Cardiology, Ospedale Civico ArnasCardiology Division, Department of Internal Medicine, National Taiwan University HospitalDivision of Cardiology, Hospital Clinico Universitario de ValenciaInterventional Cardiology Unit, Azienda Ospedaliera SanitariaCardiology Department, Hospital Garcia de OrtaDivision of Cardiology, CHU Lariboisière, AP-HP, Paris VII University, INSERM UMRS 942Instituto Cardiovascular de Buenos AiresCardiology Institute, Istanbul UniversityDivision of Cardiology Clinical and Experimental Interventional Cardiology, University of SaarlandDivision of Cardiology, Oulu University HospitalDivision of Cardiology, Hospital de Santa Cruz, CHLO-Nova Medical School, CEDOCDivision of Cardiology, Kontantopoulion HospitalDivision of Cardiology, Heart Centre TurkuDivision of Cardiology, Hospital de Santo AntónioDepartment of Teaching and Research, Instituto de Cardiología de Corrientes “Juana F. Cabral”Tyumen Cardiology Research CenterDivision of Cardiology, Ospedale “A. Manzoni”Iraklion University HospitalDivision of Cardiology, Attikon University HospitalDivision of Cardiology, Universidad UPB, Universidad CESDivision of Cardiology, Alexandra HospitalDivision of Cardiology, Groupe Hospitalier Mutualiste de GrenobleInterventional Cardiology Unit, Azienda Ospedaliero Universitaria“Ospedali Riuniti”Division of Cardiology, Hospital Puerta del MarInstituto de Cardiologia IntegralDepartment of Cardiology and Cardiovascular Interventions, Instituto Nacional de Cirugía CardíacaDepartment of Cardiology, Queen Mary Hospital, University of Hong KongDivision of Cardiology, Otamendi HospitalCardiovascular Department Pelita, Harapan University/Heart Center Siloam Lippo Village HospitalCenter Hospitalier d’Antibes Juan Les PinsDivision of Cardiology, Hospiatl CordobaDivision of Cardiology, Ospedale del MareDepartment of Statistical Sciences, University of PadovaDepartment of Cardiology, ASL 4 LiguriaDivision of Cardiology, Blida University HospitalDivision of Cardiology, Hopital Erasmus, Universitè Libre de BruxellesInstituto Cardiovascular de Buenos AiresDivision of Cardiology, Radboud University Medical CenterDivision of Cardiology, Ospedale degli Infermi, ASL BiellaAbstract Background Chronic obstructive pulmonary disease (COPD) is projected to become the third cause of mortality worldwide. COPD shares several pathophysiological mechanisms with cardiovascular disease, especially atherosclerosis. However, no definite answers are available on the prognostic role of COPD in the setting of ST elevation myocardial infarction (STEMI), especially during COVID-19 pandemic, among patients undergoing primary angioplasty, that is therefore the aim of the current study. Methods In the ISACS-STEMI COVID-19 registry we included retrospectively patients with STEMI treated with primary percutaneous coronary intervention (PCI) between March and June of 2019 and 2020 from 109 high-volume primary PCI centers in 4 continents. Results A total of 15,686 patients were included in this analysis. Of them, 810 (5.2%) subjects had a COPD diagnosis. They were more often elderly and with a more pronounced cardiovascular risk profile. No preminent procedural dissimilarities were noticed except for a lower proportion of dual antiplatelet therapy at discharge among COPD patients (98.9% vs. 98.1%, P = 0.038). With regards to short-term fatal outcomes, both in-hospital and 30-days mortality occurred more frequently among COPD patients, similarly in pre-COVID-19 and COVID-19 era. However, after adjustment for main baseline differences, COPD did not result as independent predictor for in-hospital death (adjusted OR [95% CI] = 0.913[0.658–1.266], P = 0.585) nor for 30-days mortality (adjusted OR [95% CI] = 0.850 [0.620–1.164], P = 0.310). No significant differences were detected in terms of SARS-CoV-2 positivity between the two groups. Conclusion This is one of the largest studies investigating characteristics and outcome of COPD patients with STEMI undergoing primary angioplasty, especially during COVID pandemic. COPD was associated with significantly higher rates of in-hospital and 30-days mortality. However, this association disappeared after adjustment for baseline characteristics. Furthermore, COPD did not significantly affect SARS-CoV-2 positivity. Trial registration number: NCT 04412655 (2nd June 2020).https://doi.org/10.1186/s12931-022-02128-0STEMICOPDMortality |
| spellingShingle | Giuseppe De Luca Matteo Nardin Magdy Algowhary Berat Uguz Dinaldo C. Oliveira Vladimir Ganyukov Zan Zimbakov Miha Cercek Lisette Okkels Jensen Poay Huan Loh Lucian Calmac Gerard Roura Ferrer Alexandre Quadros Marek Milewski Fortunato Scotto di Uccio Clemens von Birgelen Francesco Versaci Jurrien Ten Berg Gianni Casella Aaron Wong Sung Lung Petr Kala José Luis Díez Gil Xavier Carrillo Maurits Dirksen Victor M. Becerra-Munoz Michael Kang-yin Lee Dafsah Arifa Juzar Rodrigo de Moura Joaquim Roberto Paladino Davor Milicic Periklis Davlouros Nikola Bakraceski Filippo Zilio Luca Donazzan Adriaan Kraaijeveld Gennaro Galasso Arpad Lux Lucia Marinucci Vincenzo Guiducci Maurizio Menichelli Alessandra Scoccia Aylin Hatice Yamac Kadir Ugur Mert Xacobe Flores Rios Tomas Kovarnik Michal Kidawa Josè Moreu Vincent Flavien Enrico Fabris Iñigo Lozano Martínez-Luengas Marco Boccalatte Francisco Bosa Ojeda Carlos Arellano-Serrano Gianluca Caiazzo Giuseppe Cirrincione Hsien-Li Kao Juan Sanchis Forés Luigi Vignali Helder Pereira Stephane Manzo Santiago Ordoñez Alev Arat Özkan Bruno Scheller Heidi Lehtola Rui Teles Christos Mantis Ylitalo Antti João A. Brum Silveira Rodrigo Zoni Ivan Bessonov Stefano Savonitto George Kochiadakis Dimitrios Alexopoulos Carlos E. Uribe John Kanakakis Benjamin Faurie Gabriele Gabrielli Alejandro Gutierrez Barrios Juan Pablo Bachini Alex Rocha Frankie Chor-Cheung Tam Alfredo Rodriguez Antonia Anna Lukito Veauthyelau Saint-Joy Gustavo Pessah Andrea Tuccillo Giuliana Cortese Guido Parodi Mohamed Abed Bouraghda Elvin Kedhi Pablo Lamelas Harry Suryapranata Monica Verdoia Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry Respiratory Research STEMI COPD Mortality |
| title | Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry |
| title_full | Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry |
| title_fullStr | Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry |
| title_full_unstemmed | Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry |
| title_short | Impact of chronic obstructive pulmonary disease on short-term outcome in patients with ST-elevation myocardial infarction during COVID-19 pandemic: insights from the international multicenter ISACS-STEMI registry |
| title_sort | impact of chronic obstructive pulmonary disease on short term outcome in patients with st elevation myocardial infarction during covid 19 pandemic insights from the international multicenter isacs stemi registry |
| topic | STEMI COPD Mortality |
| url | https://doi.org/10.1186/s12931-022-02128-0 |
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inigolozanomartinezluengas impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT marcoboccalatte impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT franciscobosaojeda impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT carlosarellanoserrano impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT gianlucacaiazzo impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT giuseppecirrincione impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT hsienlikao impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT juansanchisfores impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT luigivignali impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT helderpereira impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT stephanemanzo impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT santiagoordonez impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT alevaratozkan impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT brunoscheller impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT heidilehtola impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT ruiteles impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT christosmantis impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT ylitaloantti impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT joaoabrumsilveira impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT rodrigozoni impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT ivanbessonov impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT stefanosavonitto impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT georgekochiadakis impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT dimitriosalexopoulos impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT carloseuribe impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT johnkanakakis impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT benjaminfaurie impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT gabrielegabrielli impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT alejandrogutierrezbarrios impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT juanpablobachini impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT alexrocha impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT frankiechorcheungtam impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT alfredorodriguez impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT antoniaannalukito impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT veauthyelausaintjoy impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT gustavopessah impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT andreatuccillo impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT giulianacortese impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT guidoparodi impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT mohamedabedbouraghda impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT elvinkedhi impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT pablolamelas impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT harrysuryapranata impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry AT monicaverdoia impactofchronicobstructivepulmonarydiseaseonshorttermoutcomeinpatientswithstelevationmyocardialinfarctionduringcovid19pandemicinsightsfromtheinternationalmulticenterisacsstemiregistry |