Endotoxin in Sepsis: Methods for LPS Detection and the Use of Omics Techniques

Lipopolysaccharide (LPS) or endotoxin, the major cell wall component of Gram-negative bacteria, plays a pivotal role in the pathogenesis of sepsis. It is able to activate the host defense system through interaction with Toll-like receptor 4, thus triggering pro-inflammatory mechanisms. A large amoun...

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Bibliographic Details
Main Authors: Grazia Maria Virzì, Maria Mattiotti, Massimo de Cal, Claudio Ronco, Monica Zanella, Silvia De Rosa
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/13/1/79