Sex-based differences in the distribution of Aujeszky’s disease-seropositive Japanese wild boar
Abstract Background Aujeszky’s disease virus (ADV) primarily infects domestic pigs and wild boars, causing the abortion and death of young piglets due to central nervous system disorders. In Japan, the national eradication program for ADV in domestic pigs has been successful in most prefectures; how...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-06-01
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| Series: | Porcine Health Management |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40813-023-00323-z |
| _version_ | 1797801163121229824 |
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| author | Emi Yamaguchi Michihiro Takagi Makoto Osaki Yoko Hayama Takehisa Yamamoto |
| author_facet | Emi Yamaguchi Michihiro Takagi Makoto Osaki Yoko Hayama Takehisa Yamamoto |
| author_sort | Emi Yamaguchi |
| collection | DOAJ |
| description | Abstract Background Aujeszky’s disease virus (ADV) primarily infects domestic pigs and wild boars, causing the abortion and death of young piglets due to central nervous system disorders. In Japan, the national eradication program for ADV in domestic pigs has been successful in most prefectures; however, concern has been raised regarding ADV-infected wild boars as a source of transmission to domestic pigs. Results We assessed the nationwide seroprevalence of ADV among wild boars (Sus scrofa) in Japan. Moreover, we determined the sex-based differences in the spatial clustering of seropositive animals. Serum samples were obtained from a total of 1383 wild boars acquired by hunting in 41 prefectures in three fiscal years (April–March in 2014, 2015, and 2017). Seropositivity tests for ADV using enzyme-linked immunosorbent assay, the latex agglutination and neutralization tests showed 29 boars seropositive for ADV (29/1383, 2.1% [95% confidence interval, CI: 1.4–3.0%]), with 28 of these boars originating from three prefectures in the Kii Peninsula (28/121, 23.1% [95% CI: 16.0–31.7%]). The degree of spatial clustering of these ADV-seropositive adult boars in the Kii Peninsula was evaluated using the K-function and data from sera samples of 46 (14 seropositive) male and 54 (12 seropositive) female boars. The degree of clustering among females was significantly higher in seropositive animals than in tested animals; however, such a difference was not observed for seropositive males. Conclusions The spatial dynamics of ADV among adult wild boars may be characterized based on sex, and is likely due to sex-based differences in behavioral patterns including dispersal among wild boars. |
| first_indexed | 2024-03-13T04:46:15Z |
| format | Article |
| id | doaj.art-369896fd1bb8491a89d9baac6a7bd0c5 |
| institution | Directory Open Access Journal |
| issn | 2055-5660 |
| language | English |
| last_indexed | 2024-03-13T04:46:15Z |
| publishDate | 2023-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Porcine Health Management |
| spelling | doaj.art-369896fd1bb8491a89d9baac6a7bd0c52023-06-18T11:28:21ZengBMCPorcine Health Management2055-56602023-06-019111010.1186/s40813-023-00323-zSex-based differences in the distribution of Aujeszky’s disease-seropositive Japanese wild boarEmi Yamaguchi0Michihiro Takagi1Makoto Osaki2Yoko Hayama3Takehisa Yamamoto4Epidemiology Unit, Division of Transboundary Animal Disease Research, National Institute of Animal Health, National Agriculture and Food Research OrganizationBiologicals Production Office, Department of Animal Disease Control and Prevention, National Institute of Animal Health, National Agriculture and Food Research OrganizationStrategic Planning Headquarters, National Agriculture and Food Research OrganizationEpidemiology Unit, Division of Transboundary Animal Disease Research, National Institute of Animal Health, National Agriculture and Food Research OrganizationEpidemiology Unit, Division of Transboundary Animal Disease Research, National Institute of Animal Health, National Agriculture and Food Research OrganizationAbstract Background Aujeszky’s disease virus (ADV) primarily infects domestic pigs and wild boars, causing the abortion and death of young piglets due to central nervous system disorders. In Japan, the national eradication program for ADV in domestic pigs has been successful in most prefectures; however, concern has been raised regarding ADV-infected wild boars as a source of transmission to domestic pigs. Results We assessed the nationwide seroprevalence of ADV among wild boars (Sus scrofa) in Japan. Moreover, we determined the sex-based differences in the spatial clustering of seropositive animals. Serum samples were obtained from a total of 1383 wild boars acquired by hunting in 41 prefectures in three fiscal years (April–March in 2014, 2015, and 2017). Seropositivity tests for ADV using enzyme-linked immunosorbent assay, the latex agglutination and neutralization tests showed 29 boars seropositive for ADV (29/1383, 2.1% [95% confidence interval, CI: 1.4–3.0%]), with 28 of these boars originating from three prefectures in the Kii Peninsula (28/121, 23.1% [95% CI: 16.0–31.7%]). The degree of spatial clustering of these ADV-seropositive adult boars in the Kii Peninsula was evaluated using the K-function and data from sera samples of 46 (14 seropositive) male and 54 (12 seropositive) female boars. The degree of clustering among females was significantly higher in seropositive animals than in tested animals; however, such a difference was not observed for seropositive males. Conclusions The spatial dynamics of ADV among adult wild boars may be characterized based on sex, and is likely due to sex-based differences in behavioral patterns including dispersal among wild boars.https://doi.org/10.1186/s40813-023-00323-zWild boarAujeszky’s disease virusSex-based differenceSpatial clusteringNational serosurveyK-function |
| spellingShingle | Emi Yamaguchi Michihiro Takagi Makoto Osaki Yoko Hayama Takehisa Yamamoto Sex-based differences in the distribution of Aujeszky’s disease-seropositive Japanese wild boar Porcine Health Management Wild boar Aujeszky’s disease virus Sex-based difference Spatial clustering National serosurvey K-function |
| title | Sex-based differences in the distribution of Aujeszky’s disease-seropositive Japanese wild boar |
| title_full | Sex-based differences in the distribution of Aujeszky’s disease-seropositive Japanese wild boar |
| title_fullStr | Sex-based differences in the distribution of Aujeszky’s disease-seropositive Japanese wild boar |
| title_full_unstemmed | Sex-based differences in the distribution of Aujeszky’s disease-seropositive Japanese wild boar |
| title_short | Sex-based differences in the distribution of Aujeszky’s disease-seropositive Japanese wild boar |
| title_sort | sex based differences in the distribution of aujeszky s disease seropositive japanese wild boar |
| topic | Wild boar Aujeszky’s disease virus Sex-based difference Spatial clustering National serosurvey K-function |
| url | https://doi.org/10.1186/s40813-023-00323-z |
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